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关节内注射非甾体抗炎药(酮咯酸)与注射透明质酸治疗粘连性肩周炎时疼痛评分平均降低情况(根据加州大学洛杉矶分校肩部评分量表)的比较。

Comparison of intra articular NSAID (ketorolac) injection versus hyaluronic acid injection for the mean decrease of pain score (according to UCLA shoulder rating scale) in the management of adhesive capsulitis.

作者信息

Akhtar Muhammad, Nadeem Rana Dil Awaiz, Shah Gillani Syed Farazul-Hassan, Cheema Omer Iqbal, Nadeem Mohammed Rajaab

机构信息

Department of Orthopedics Surgery, Unit- II, King Edward Medical University / Mayo Hospital, Lahore, Pakistan.

University of Pittsburg, USA.

出版信息

Pak J Pharm Sci. 2019 May;32(3):953-956.

PMID:31278705
Abstract

Adhesive capsulitis is painful condition, associated with gradual loss of active and passive shoulder motion that has a disabling capability. In this study we compared the short term outcome by measuring the mean decrease of pain in adhesive capsulitis using University of California Los-Angeles (UCLA) shoulder rating scale after intra-articular Non-Steroidal Anti Inflammatory Drug (NSAID) Ketorolac and Hyaluronic acid injection. This Randomized controlled trial was carried out using non probability consecutive sampling technique from 1st November 2015 to 30th April 2016. Total 160 patients with adhesive capsulitis for six months' age between 18 to 70 years were taken and randomly divided into two equal groups by computer allocation method. The 80 patients in Group A received Intra-articular (NSAID) Ketorolac injection while patients in Group B were given Intra-articular Hyaluronic acid. Pain score for both the groups were recorded using UCLA shoulder rating scale before treatment and then at follow up after a period of 4 weeks. Out of total 160 cases, 47.5% (n=38) in Group A and 45% (n=36) in Group B were male whereas 52.5% (n=42) in Group A and 55% (n=44) in Group B were females. Most commonly affected age group with 40% (n=32) participants was aged between 51 - 60 years. Mean age of Group A was 37.87±1.027 and in Group B was 45.37±5.743. Interestingly 60% (n=48) of Group A and 55% (n=44) of Group B had involvement of the right shoulder. Pre-treatment UCLA pain score was calculated to be 14.90±4.969 in Group-A and 15.16±5.578 in Group-B. Final post treatment UCLA score was 26.67±2.331 in Group A and 21.72±3.838 in Group B. The mean decrease of pain in Adhesive capsulitis using UCLA rating scale was significantly better in NSAID group as compared to Hyaluronic acid group.

摘要

粘连性囊炎是一种疼痛性疾病,伴有肩关节主动和被动活动逐渐丧失,具有致残性。在本研究中,我们通过使用加州大学洛杉矶分校(UCLA)肩关节评分量表测量关节内注射非甾体抗炎药酮咯酸和透明质酸后粘连性囊炎患者疼痛的平均减轻程度,比较了短期疗效。本随机对照试验于2015年11月1日至2016年4月30日采用非概率连续抽样技术进行。共纳入160例病程6个月、年龄在18至70岁之间的粘连性囊炎患者,并通过计算机分配方法随机分为两组。A组的80例患者接受关节内注射(非甾体抗炎药)酮咯酸,而B组的患者接受关节内注射透明质酸。两组患者在治疗前及4周后的随访时均使用UCLA肩关节评分量表记录疼痛评分。在总共160例病例中,A组47.5%(n = 38)为男性,B组45%(n = 36)为男性;A组52.5%(n = 42)为女性,B组55%(n = 44)为女性。最常受累的年龄组有40%(n = 32)的参与者年龄在51至60岁之间。A组的平均年龄为37.87±1.027,B组为

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