急性器官损伤和纤维化中的细胞死亡。
Cell Death in Acute Organ Injury and Fibrosis.
机构信息
Department of Immunology, Mie University Faculty and Graduate School of Medicine, Edobashi 2-174, Tsu 514-8507, Japan.
Department of Diabetes and Endocrinology, Mie University Faculty and Graduate School of Medicine, Edobashi 2-174, Tsu 514-8507, Japan.
出版信息
Int J Mol Sci. 2024 Apr 1;25(7):3930. doi: 10.3390/ijms25073930.
Abstract
Tissue fibrosis is characterized by the excessive accumulation of extracellular matrix in various organs, including the lungs, liver, skin, kidneys, pancreas, and heart, ultimately leading to organ failure [...].
摘要
组织纤维化的特征是各种器官（包括肺、肝、皮肤、肾、胰腺和心脏）中细胞外基质的过度积累，最终导致器官衰竭[...]。
相似文献
1
Cell Death in Acute Organ Injury and Fibrosis.急性器官损伤和纤维化中的细胞死亡。
Int J Mol Sci. 2024 Apr 1;25(7):3930. doi: 10.3390/ijms25073930.
2
Targeting the renin-angiotensin-aldosterone system in fibrosis.靶向肾素-血管紧张素-醛固酮系统治疗纤维化。
Matrix Biol. 2020 Sep;91-92:92-108. doi: 10.1016/j.matbio.2020.04.005. Epub 2020 May 16.
3
Featured Article: TGF-β1 dominates extracellular matrix rigidity for inducing differentiation of human cardiac fibroblasts to myofibroblasts.特色文章：TGF-β1 通过控制细胞外基质硬度诱导人心肌成纤维细胞分化为肌成纤维细胞。
Exp Biol Med (Maywood). 2018 Apr;243(7):601-612. doi: 10.1177/1535370218761628. Epub 2018 Mar 4.
4
Organ and tissue fibrosis: Molecular signals, cellular mechanisms and translational implications.器官和组织纤维化：分子信号、细胞机制及转化意义。
Mol Aspects Med. 2019 Feb;65:2-15. doi: 10.1016/j.mam.2018.06.003. Epub 2018 Jun 30.
5
DNA methylation regulated gene expression in organ fibrosis.DNA 甲基化调控器官纤维化中的基因表达。
Biochim Biophys Acta Mol Basis Dis. 2017 Sep;1863(9):2389-2397. doi: 10.1016/j.bbadis.2017.05.010. Epub 2017 May 10.
6
The controversial role of mast cells in fibrosis.肥大细胞在纤维化中的争议性作用。
Immunol Rev. 2018 Mar;282(1):198-231. doi: 10.1111/imr.12626.
7
Microvascular targets for anti-fibrotic therapeutics.抗纤维化治疗的微血管靶点。
Yale J Biol Med. 2013 Dec 13;86(4):537-54.
8
Metformin and Fibrosis: A Review of Existing Evidence and Mechanisms.二甲双胍与纤维化：现有证据与作用机制的综述。
J Diabetes Res. 2021 Apr 29;2021:6673525. doi: 10.1155/2021/6673525. eCollection 2021.
9
Peptide mediated therapy in fibrosis: Mechanisms, advances and prospects.肽介导的纤维化治疗：机制、进展与展望。
Biomed Pharmacother. 2023 Jan;157:113978. doi: 10.1016/j.biopha.2022.113978. Epub 2022 Nov 21.
10
MicroRNAs in organ fibrosis: From molecular mechanisms to potential therapeutic targets.微小 RNA 在器官纤维化中的作用：从分子机制到潜在的治疗靶点。
Pathol Res Pract. 2021 Sep;225:153588. doi: 10.1016/j.prp.2021.153588. Epub 2021 Aug 13.
引用本文的文献
1
P4HA1: an important target for treating fibrosis related diseases and cancer.脯氨酰-4-羟化酶α1亚基：治疗纤维化相关疾病和癌症的重要靶点。
Front Pharmacol. 2024 Nov 6;15:1493420. doi: 10.3389/fphar.2024.1493420. eCollection 2024.
本文引用的文献
1
Idiopathic Pulmonary Fibrosis: Where do We Stand and How Far to Go?特发性肺纤维化：我们处于何种境地，又该走向何方？
Discov Med. 2024 Jan;36(180):22-47. doi: 10.24976/Discov.Med.202436180.3.
2
Cell death.细胞死亡。
Cell. 2024 Jan 18;187(2):235-256. doi: 10.1016/j.cell.2023.11.044.
3
Control of Cell Death in Health and Disease.细胞死亡的调控在健康与疾病中的作用
Annu Rev Pathol. 2024 Jan 24;19:157-180. doi: 10.1146/annurev-pathmechdis-051022-014433. Epub 2023 Oct 3.
4
Programmed Cell Death in Liver Fibrosis.肝纤维化中的程序性细胞死亡
J Inflamm Res. 2023 Sep 1;16:3897-3910. doi: 10.2147/JIR.S427868. eCollection 2023.
5
From Inflammation to Resolution: Specialized Pro-resolving Mediators in Posttraumatic Osteoarthritis.从炎症到解决：创伤后骨关节炎中的特异性促解决介质。
Curr Osteoporos Rep. 2023 Dec;21(6):758-770. doi: 10.1007/s11914-023-00817-3. Epub 2023 Aug 24.
6
Inhibition of the NF-κB Signaling Pathway Alleviates Pyroptosis in Bladder Epithelial Cells and Neurogenic Bladder Fibrosis.抑制 NF-κB 信号通路可减轻膀胱上皮细胞焦亡和神经源性膀胱纤维化。
Int J Mol Sci. 2023 Jul 6;24(13):11160. doi: 10.3390/ijms241311160.
7
Mechanisms of organ fibrosis: Emerging concepts and implications for novel treatment strategies.器官纤维化的机制：新观点与新型治疗策略的启示。
Mol Aspects Med. 2023 Aug;92:101191. doi: 10.1016/j.mam.2023.101191. Epub 2023 May 24.
8
Amelioration of Pulmonary Fibrosis by Matrix Metalloproteinase-2 Overexpression.基质金属蛋白酶-2 过表达对肺纤维化的改善作用。
Int J Mol Sci. 2023 Apr 3;24(7):6695. doi: 10.3390/ijms24076695.
9
Inhibition of a Microbiota-Derived Peptide Ameliorates Established Acute Lung Injury.抑制微生物群衍生肽可改善已确立的急性肺损伤。
Am J Pathol. 2023 Jun;193(6):740-754. doi: 10.1016/j.ajpath.2023.03.003. Epub 2023 Mar 23.
10
Selective CB Receptor Agonist, HU-308, Reduces Systemic Inflammation in Endotoxin Model of Pneumonia-Induced Acute Lung Injury.选择性 CB 受体激动剂 HU-308 可减轻肺炎相关性急性肺损伤内毒素模型中的全身炎症反应。
Int J Mol Sci. 2022 Dec 13;23(24):15857. doi: 10.3390/ijms232415857.
Zotero 插件