DelRosso Lourdes M, Panek David, Mackintosh Erin, White Klane, Redding Greg
University of Washington, Seattle, WA, USA.
Seattle Children's Hospital, Seattle, WA, USA.
Sleep Breath. 2024 Aug;28(4):1777-1780. doi: 10.1007/s11325-024-03029-w. Epub 2024 Apr 16.
Patients with early onset scoliosis are at high risk of sleep disordered breathing, sleep disruption, and adverse consequences of poor sleep. In this study, we aim to assess the prevalence of periodic limb movements of sleep in a cohort of children with early onset scoliosis and identify factors that correlate with the presence of periodic limb movements.
This is a retrospective chart review of 40 patients with EOS (ages 1-17 years) who underwent a PSG from 2003 through 2019. Data collected included age, sex, and polysomnography parameters. Descriptive statistics were used: independent T test and Pearson correlation.
The average age was 9.6 years (SD 5.2); 22 were female. Eleven patients (27.5%) had elevated periodic limb movement index (PLMI) (≥ 5). Those with PLMI ≥ 5 had arousal index of 15.4 (SD 7.2) and those with normal PLMI having an arousal index of 9.4 (SD 4.9); this reached statistical significance (p < 0.05). Those with elevated PLMI spent 4.9 (SD 8.3) minutes with saturations below 88%, while those with normal PLMI spent 1.0 (SD 1.8); this was statistically significant. There was a moderate positive correlation between arousal index, hypoxemia, and PLMI.
The study suggests that children with early onset scoliosis have higher frequency of periodic limb movements during sleep, and these may be correlated with increased arousal and with hypoxemia.
早发性脊柱侧弯患者存在睡眠呼吸障碍、睡眠中断及睡眠不佳带来的不良后果的高风险。在本研究中，我们旨在评估一组早发性脊柱侧弯儿童中睡眠周期性肢体运动的患病率，并确定与睡眠周期性肢体运动存在相关的因素。
这是一项对40例早发性脊柱侧弯患者（年龄1至17岁）进行的回顾性图表审查，这些患者在2003年至2019年期间接受了多导睡眠图检查。收集的数据包括年龄、性别和多导睡眠图参数。使用描述性统计方法：独立t检验和Pearson相关性分析。
平均年龄为9.6岁（标准差5.2）；22例为女性。11例患者（27.5%）的睡眠周期性肢体运动指数（PLMI）升高（≥5）。PLMI≥5的患者觉醒指数为15.4（标准差7.2），PLMI正常的患者觉醒指数为9.4（标准差4.9）；这具有统计学意义（p<0.05）。PLMI升高的患者血氧饱和度低于88%的时间为4.9（标准差8.3）分钟，而PLMI正常的患者为1.0（标准差1.8）分钟；这具有统计学意义。觉醒指数、低氧血症和PLMI之间存在中度正相关。
该研究表明，早发性脊柱侧弯儿童睡眠期间周期性肢体运动的频率较高，且这些运动可能与觉醒增加和低氧血症相关。
