Korean Center for the Validation of Alternative Methods (KoCVAM), Toxicological Screening and Testing Division, Toxicological Evaluation and Research Department, National Institute of Food and Drug Safety Evaluation, Ministry of Food and Drug Safety, Cheongju-si, Republic of Korea.
Altern Lab Anim. 2024 May;52(3):166-176. doi: 10.1177/02611929241244520. Epub 2024 Apr 16.
The Korean Center for the Validation of Alternative Methods (KoCVAM), which promotes the Three Rs principles and the use of alternative methods in Korea, has been operating within the Toxicological Screening and Testing Division of the Ministry of Food and Drug Safety (MFDS) since 2009. KoCVAM has exchanged opinions and information on the development and validation of non-animal alternative test methods as part of the International Cooperation on Alternative Test Methods (ICATM), and provided input into draft OECD Test Guidelines (TGs). Several Korean laws (e.g. the ) encourage the use of alternative test methods for chemical testing and assessment. To promote and support the use of alternative test methods in the country, KoCVAM has published information and provided training on the national guidelines, which are based on the OECD TGs. In addition, KoCVAM has held annual training workshops on alternative test methods, to help Korean research institutions (including GLP test facilities) to implement them. In addition, by helping to develop and validate alternative test methods that were adopted in OECD TG 442B, TG 492 and TG 439, KoCVAM has contributed to the enhanced competitiveness of Korean industry on the worldwide stage.
韩国替代方法验证中心（KoCVAM）自 2009 年以来一直在食品药品安全部（MFDS）的毒理学筛选和测试司内运作，推广 3R 原则和替代方法在韩国的应用。KoCVAM 作为替代方法国际合作组织（ICATM）的一部分，就替代方法的开发和验证交换了意见和信息，并为经合组织测试指南（TGs）草案提供了投入。韩国的几部法律（例如《化管法》）鼓励在化学品测试和评估中使用替代测试方法。为了在全国推广和支持替代测试方法的应用，KoCVAM 根据经合组织 TG 出版了有关国家指南的信息并提供了相关培训。此外，KoCVAM 还举办了替代测试方法年度培训研讨会，以帮助韩国研究机构（包括 GLP 测试设施）实施这些方法。此外，通过帮助开发和验证经合组织 TG 442B、TG 492 和 TG 439 中采用的替代测试方法，KoCVAM 增强了韩国产业在全球舞台上的竞争力。
