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一名儿科患者的上颌前部成釉细胞纤维瘤:病例报告

Anterior Maxillary Ameloblastic Fibroma in a Pediatric Patient: A Case Report.

作者信息

Daoudi Selma, Hariri Elmehdi, Ramdi Hind

机构信息

Pediatric Dentistry, Mohammed V University in Rabat, Rabat, MAR.

Dentistry, Mohammed V University in Rabat, Rabat, MAR.

出版信息

Cureus. 2025 Apr 24;17(4):e82918. doi: 10.7759/cureus.82918. eCollection 2025 Apr.

Abstract

Ameloblastic fibroma (AF) is a rare benign mixed odontogenic tumor, more frequently observed in children and adolescents. It typically develops in the posterior region of the mandible. Radiographically, it appears as a well-defined radiolucent lesion, requiring histological confirmation to differentiate it from other odontogenic tumors. We report the case of an eight-year-old male patient in good general health who presented following an anterior trauma. The extraoral examination was normal, while the intraoral examination revealed the avulsion of tooth 11, a complicated enamel-dentin fracture of tooth 21, and a firm palatal swelling. Radiographic evaluation showed a unilocular radiolucent lesion containing radiopaque structures, initially suggesting a diagnosis of compound odontoma. Complete enucleation of the lesion revealed calcified components and soft tissue. Histopathological analysis confirmed the diagnosis of AF. A conservative enucleation was performed due to the well-defined margins of the lesion, along with apexification of the adjacent permanent tooth 21. A six-month postoperative follow-up showed satisfactory bone healing with no signs of recurrence. Given that this fibroma presents a potential for recurrence and malignant transformation, rigorous long-term follow-up is essential. This case highlights the importance of thorough clinical, radiographic, and histological evaluation of jaw lesions in pediatric patients, as well as the necessity of long-term follow-up to ensure early detection of any complications.

摘要

成釉细胞纤维瘤(AF)是一种罕见的良性牙源性混合瘤,多见于儿童和青少年。它通常在下颌骨后部区域发生。在影像学上,它表现为边界清晰的透射性病变,需要组织学确诊以将其与其他牙源性肿瘤区分开来。我们报告一例8岁男性患者,全身状况良好,因前部外伤前来就诊。口外检查正常,而口内检查发现11号牙脱落,21号牙釉质 - 牙本质复合骨折,以及硬腭有坚实的肿胀。影像学评估显示一个单房透射性病变,内含不透射线结构,最初提示诊断为复合性牙瘤。病变的完整摘除显示有钙化成分和软组织。组织病理学分析确诊为AF。由于病变边界清晰,对相邻的恒牙21号进行了根尖诱导成形术,并进行了保守性摘除。术后6个月随访显示骨愈合良好,无复发迹象。鉴于这种纤维瘤有复发和恶变的可能,严格的长期随访至关重要。本病例强调了对儿科患者颌骨病变进行全面临床、影像学和组织学评估的重要性,以及长期随访以确保早期发现任何并发症的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7833/12103704/0e86ed4dd0bf/cureus-0017-00000082918-i01.jpg

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本文引用的文献

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Ameloblastic fibroma with extensive dentinoid - A rare presentation.伴有广泛类牙本质的成釉细胞纤维瘤——一种罕见表现。
J Oral Maxillofac Pathol. 2023 Oct-Dec;27(4):760-764. doi: 10.4103/jomfp.jomfp_200_23. Epub 2023 Dec 20.
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Ameloblastic fibroma: A case report.成釉细胞纤维瘤:一例病例报告。
J Oral Maxillofac Pathol. 2023 Feb;27(Suppl 1):S60-S63. doi: 10.4103/jomfp.jomfp_337_22. Epub 2023 Feb 4.
6
Ameloblastic Fibroma in Mandibular Anterior Tooth Region: A Case Report.下颌前牙区的成釉细胞瘤:病例报告。
Bull Tokyo Dent Coll. 2021 Mar 13;62(1):49-54. doi: 10.2209/tdcpublication.2020-0031. Epub 2021 Feb 15.
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Ameloblastic fibroma in a young adult.一名年轻成年人的成釉细胞纤维瘤。
J Oral Maxillofac Pathol. 2019 Feb;23(Suppl 1):63-65. doi: 10.4103/jomfp.JOMFP_37_16.
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Ameloblastic fibroma: an uncommon entity.成釉细胞纤维瘤:一种罕见的病变。
BMJ Case Rep. 2013 Jul 9;2013:bcr2013010279. doi: 10.1136/bcr-2013-010279.

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