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乳腺癌患者使用 Serasynth 和 SeragynBR 合成补片行即刻乳房重建:单中心经验、并发症分析。

Immediate breast reconstruction in breast cancer patients with the use of Serasynth and SeragynBR synthetic meshes. Single-oncological center experience, analysis of complications.

机构信息

Department of Breast Cancer and Reconstructive Surgery, Maria Sklodowska Curie Memorial Cencer Center and Institute of Oncology, Warsaw, Poland.

出版信息

Pol Przegl Chir. 2023 Oct 12;96(2):11-20. doi: 10.5604/01.3001.0016.3172.

DOI:10.5604/01.3001.0016.3172
PMID:38629281
Abstract

<br><b>Introduction:</b> The use of meshes in mastectomies with immediate breast reconstruction (IBR) has become the gold standard.</br> <br><b>Aim:</b> The use of meshes in mastectomies with immediate breast reconstruction (IBR) has become a gold standard. The purpose of the study was to analyze the complications and own experience with the use of Serasynth fully absorbable and SeragynBR partially absorbable synthetic meshes.</br> <br><b>Material and methods:</b> In the period from December 2017 to July 2020, 118 IBR were performed in the Author's Department with the use of SeragynBR and Serasynth meshes in 93 patients operated for breast cancer. 78 Serasynth meshes (Group 1) and 40 SeragynBR meshes (Group 2) were implanted.</br> <br><b>Results:</b> The most common complication was persistent seroma collection, which was reported in 17.9% of cases in Group 1 and 25% in Group 2. Skin inflammation was reported in 7.6% and 17.5%, while infections in 2.5% and 5% of the operated breasts in Group 1 and Group 2. Reoperation was required in 5.1% and 5% of the patients in Group 1 and Group 2. The percentage of complications was lower when Serasynth rather than Seragyn BR meshes were implanted. The frequent incidence of the seroma collection did not contribute in any significant way to serious complications such as removal of mesh/implant or infection. The complications, which developed following the implantation of both mesh types, were similar to those presented in other publications concerning mastectomy with IBR with the use of synthetic meshes. The percentage of implant losses/explanations in the discussed groups was lower than that reported in the literature.</br> <br><b>Conclusion:</b> Despite the complications, both types of meshes can be considered as safe additions to reconstructive breast surgeries.</br> <br><b>Level of Evidence:</b> Level III.</br&gt.

摘要

引言: 在即刻乳房重建(IBR)乳房切除术使用网片已成为金标准。


目的: 在即刻乳房重建(IBR)乳房切除术中使用网片已成为金标准。本研究的目的是分析使用完全可吸收的 Serasynth 和部分可吸收的 SeragynBR 合成网片的并发症,并介绍作者的使用经验。


材料和方法: 2017 年 12 月至 2020 年 7 月,作者所在部门对 93 例乳腺癌患者进行了 118 例 IBR,其中 78 例使用 Serasynth 网片(第 1 组),40 例使用 SeragynBR 网片(第 2 组)。


结果: 最常见的并发症是持续性血清肿积液,第 1 组报告为 17.9%,第 2 组为 25%。第 1 组和第 2 组皮肤炎症分别为 7.6%和 17.5%,感染分别为 2.5%和 5%。第 1 组和第 2 组分别有 5.1%和 5%的患者需要再次手术。使用 Serasynth 网片而非 Seragyn BR 网片的患者,并发症的发生率较低。血清肿积液的频繁发生并没有导致严重并发症,如网片/植入物取出或感染。植入两种网片后出现的并发症与其他关于使用合成网片行即刻乳房重建乳房切除术的文献报道相似。在讨论的两组中,植入物丢失/解释的百分比低于文献报道。


结论: 尽管存在并发症,但这两种类型的网片都可以被认为是安全的乳房重建手术的附加物。


证据等级: 三级。

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