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COVID-19 大流行期间子宫肌瘤手术治疗中的种族差异。

Racial Disparities in Surgical Treatment of Uterine Fibroids During the COVID-19 Pandemic.

机构信息

Division of Obstetrics and Gynecology, Baystate Medical Center, Springfield, Massachusetts, USA.

Epidemiology/Biostatistics Research Core, Office of Research, Baystate Medical Center, Springfield, Massachusetts, USA.

出版信息

J Womens Health (Larchmt). 2024 Aug;33(8):1085-1094. doi: 10.1089/jwh.2023.0826. Epub 2024 Apr 17.

Abstract

Analyze the association between race and surgery performed for uterine fibroids during the coronavirus disease 2019 (COVID-19) pandemic. Retrospective exploratory cross-sectional study of patients with fibroids who underwent surgery during the COVID-19 pandemic. We compared the type of surgery performed (minimally invasive hysterectomy [MIH], uterine-sparing procedure [USP], or total abdominal hysterectomy [TAH]) by White versus non-White patients. Absolute percentage differences were estimated with multinomial logistic regression adjusting for age, body mass index (BMI), parity, comorbidities, and maximum fibroid diameter. Of 350 subjects, the racial composition was 1.7% Asian, 23.4% Black, and 74.9% White. Non-White patients had greater fibroid burden by mean maximum fibroid diameter, mean uterine weight, and mean fibroid weight. Although MIH occurred more frequently among White patients (7.5% points higher [95% confidence interval (CI) = -3.1 to 18.2]), USP and TAH were more commonly conducted for non-White patients (3.4% points higher [95% CI = -10.4 to 3.6] and 4.2% points higher [95% CI = -13.2 to 4.8], respectively). The overall complication rate was 18.6%, which was 6% points lower (95% CI = -15.8 to 3.7) among White patients. During the COVID-19 pandemic at a single-site institution, non-White patients were more likely to undergo a uterine-sparing procedure for surgical treatment of uterine fibroids, abdominal procedures, including both hysterectomy and myomectomy, and experience surgery-related complications.

摘要

分析在 2019 年冠状病毒病(COVID-19)大流行期间,种族与子宫纤维瘤手术之间的关联。这是一项针对 COVID-19 大流行期间接受手术的纤维瘤患者的回顾性探索性横断面研究。我们比较了白人患者与非白人患者接受的手术类型(微创子宫切除术[MIH]、保留子宫的手术[USP]或全子宫切除术[TAH])。采用多变量逻辑回归调整年龄、体重指数(BMI)、产次、合并症和最大肌瘤直径,估计绝对百分比差异。在 350 名受试者中,种族构成为 1.7%亚洲人、23.4%黑人、74.9%白人。非白人患者的最大肌瘤直径、子宫重量和肌瘤重量平均值较大。尽管白人患者 MIH 的发生率较高(高出 7.5%点[95%置信区间(CI)=-3.1 至 18.2]),但 USP 和 TAH 更常用于非白人患者(高出 3.4%点[95%CI=-10.4 至 3.6]和高出 4.2%点[95%CI=-13.2 至 4.8])。总体并发症发生率为 18.6%,白人患者的并发症发生率低 6%点(95%CI=-15.8 至 3.7)。在单一机构的 COVID-19 大流行期间,非白人患者更有可能接受 USP 手术治疗子宫纤维瘤,而白人患者则更倾向于接受子宫切除术和子宫肌瘤切除术等腹部手术,且更容易出现与手术相关的并发症。

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