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子宫肌瘤的外科治疗:不断变化的格局。

Surgical Management of Fibroids: A Changing Landscape.

机构信息

Obstetrics and Gynecology, Northwestern Feinberg School of Medicine, Chicago, IL, USA.

Obstetrics and Gynecology, Washington University in St. Louis, St. Louis, MO, USA.

出版信息

J Womens Health (Larchmt). 2024 Nov;33(11):1528-1535. doi: 10.1089/jwh.2024.0131. Epub 2024 Oct 7.

DOI:10.1089/jwh.2024.0131
PMID:39375044
Abstract

Uterine fibroids affect patients' quality of life and contribute significantly to health care costs. Studies from 2009 to 2011 demonstrated that fibroids disproportionately affect Black women, with lower odds of uterine preservation and minimally invasive approaches. This is a retrospective cohort study of data abstracted from the National Surgical Quality Improvement Program database from 2015 to 2019 examining trends in surgical management of uterine fibroids and exploring disparities in surgical approach in a modern cohort. In total, 52,909 women underwent hysterectomy and 15,485 women underwent myomectomy between 2015 and 2019. Over the study period, the overall number of surgeries for fibroids increased by 44.2% with minimally invasive hysterectomy responsible for the majority of this increase. The proportion of patients who underwent myomectomy significantly increased (20.85% to 24.62%, value <0.0001), whereas hysterectomy significantly decreased (79.15% to 75.38%, value <0.0001). Bivariate analysis identified younger age, non-White race, and body mass index (BMI) <25 as significantly associated with performance of myomectomy. Non-Hispanic Black (adjusted odds ratio [aOR]: 3.55, 95% confidence interval [CI]: 3.23-3.89), Asian (aOR: 3.26, 95% CI: 2.80-3.80), and Hispanic Black (aOR: 5.50, 95% CI: 3.29-9.25) women were more likely to undergo myomectomy than non-Hispanic White women. Surgical treatment for fibroids increased over time, shifting toward uterine preservation. Myomectomy performance is associated with lower age and BMI and identifying as a racial and/or ethnic minority. These trends may represent improved access to surgical treatment of fibroids, resulting from the growth of minimally invasive gynecological surgery as a specialty and advocacy for equitable health care for all patients.

摘要

子宫肌瘤会影响患者的生活质量,并对医疗保健成本产生重大影响。2009 年至 2011 年的研究表明,子宫肌瘤 disproportionately 影响黑人女性,她们保留子宫和采用微创方法的几率较低。这是一项回顾性队列研究,从 2015 年至 2019 年从国家手术质量改进计划数据库中提取数据,研究子宫肌瘤手术治疗趋势,并在现代队列中探索手术方法的差异。总共,52909 名女性接受了子宫切除术,15485 名女性接受了子宫肌瘤切除术。在研究期间,子宫肌瘤手术总数增加了 44.2%,微创子宫切除术是导致这种增加的主要原因。接受子宫肌瘤切除术的患者比例显著增加(20.85%至 24.62%,value<0.0001),而子宫切除术显著减少(79.15%至 75.38%,value<0.0001)。双变量分析确定年龄较小、非白人种族和 BMI<25 与进行子宫肌瘤切除术显著相关。非西班牙裔黑人(调整后的优势比[aOR]:3.55,95%置信区间[CI]:3.23-3.89)、亚洲人(aOR:3.26,95% CI:2.80-3.80)和西班牙裔黑人(aOR:5.50,95% CI:3.29-9.25)女性比非西班牙裔白人女性更有可能接受子宫肌瘤切除术。随着时间的推移,子宫肌瘤的手术治疗有所增加,转向保留子宫。子宫肌瘤切除术与年龄较小和 BMI 较低以及认定为种族和/或少数民族有关。这些趋势可能代表着微创手术妇科作为一个专业的发展以及为所有患者提供公平医疗保健的倡导,使子宫肌瘤的手术治疗机会得到改善。

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