Faculty of Medicine and Health Technology, Tampere University, Tampere, Finland.
Department of Pediatrics, Tampere University Hospital, Tampere, Finland.
J Pediatr Gastroenterol Nutr. 2024 Jun;78(6):1287-1296. doi: 10.1002/jpn3.12220. Epub 2024 Apr 17.
Prior studies on the psychological well-being in pediatric inflammatory bowel disease (PIBD) have reported controversial results. Our aim was to compare the psychological well-being and lifestyle factors in patients with PIBD and their controls and to assess the role of contributing disease characteristics.
This cross-sectional study included 60 PIBD patients aged 6-17 years (26 with Crohn's disease [CD], 34 with ulcerative colitis [UC] or unclassified colitis [IBD-U]) from two university hospitals in Finland, and their age- and sex-matched healthy controls. Psychological well-being was assessed with three measures: a questionnaire on overall psychological well-being (PSWB) and for adolescents also Beck Depression Inventory (BDI Ia) and Perceived Stress Scale (PSS). In addition to disease characteristics and pain, we assessed physical activity, sleep, screen time, and social well-being.
Controls were more likely of stressing more (odds ratio [OR] = 3.67, 95% confidence interval [95% CI] 95% CI = 1.02-13.14), but other measures of psychological well-being did not differ statistically significantly between patients and controls. In CD, a clinically more active disease associated with inferior psychological well-being in adolescents (BDI [ρ = 0.63, p = 0.021], PSS [ρ = 0.70, p = 0.008], PSWB [ρ = 0.56, p = 0.049]). Longer time from diagnosis correlated with better psychological well-being on BDI (ρ = -0.39, p = 0.024) and PSS (ρ = -0.38, p = 0.034). Lifestyle was more sedentary in PIBD (less physical activity in children OR = 0.82, 95% CI = 0.68-0.99 and more screen time in adolescents OR = 1.18, 95% CI = 1.00-1.40).
Although the clinical features of PIBD are potentially a burden for psychological well-being, many young patients cope well with their disease. Individual variation in well-being is remarkable, making supportive measures challenging.
先前关于儿科炎症性肠病（PIBD）心理幸福感的研究结果存在争议。我们的目的是比较 PIBD 患者及其对照者的心理幸福感和生活方式因素，并评估相关疾病特征的作用。
这项横断面研究纳入了芬兰两所大学医院的 60 名 6-17 岁的 PIBD 患者（26 名克罗恩病[CD]，34 名溃疡性结肠炎[UC]或未分类结肠炎[IBD-U]），以及年龄和性别匹配的健康对照者。使用三种措施评估心理幸福感：总体心理幸福感问卷（PSWB），以及青少年使用贝克抑郁量表（BDI Ia）和感知压力量表（PSS）。除疾病特征和疼痛外，我们还评估了身体活动、睡眠、屏幕时间和社交幸福感。
与对照者相比，对照者更有可能感到压力（比值比[OR] = 3.67，95%置信区间[95%CI] 95%CI = 1.02-13.14），但患者与对照者之间在其他心理幸福感措施上并无统计学差异。在 CD 中，与青少年心理幸福感较差相关的更具临床活动性的疾病（BDI [ρ = 0.63，p = 0.021]，PSS [ρ = 0.70，p = 0.008]，PSWB [ρ = 0.56，p = 0.049]）。从诊断到现在的时间与 BDI（ρ = -0.39，p = 0.024）和 PSS（ρ = -0.38，p = 0.034）的心理幸福感呈负相关。PIBD 患者的生活方式更为久坐（儿童体力活动较少 OR = 0.82，95%CI = 0.68-0.99，青少年屏幕时间较多 OR = 1.18，95%CI = 1.00-1.40）。
尽管 PIBD 的临床特征可能对心理幸福感构成负担，但许多年轻患者仍能很好地应对疾病。幸福感的个体差异显著，这使得支持性措施具有挑战性。
