Institute of Food Safety, Animal Health and Environment "BIOR", Riga, Latvia.
Faculty of Chemistry, University of Latvia, Riga, Latvia.
Food Addit Contam Part B Surveill. 2024 Jun;17(2):180-192. doi: 10.1080/19393210.2024.2332516. Epub 2024 Apr 17.
The market demand for herbal dietary supplements is rapidly growing and such products are becoming more common and accessible to consumers. However, the knowledge about their safety remains incomplete. Herbal dietary supplements are one of the food groups that can contribute significantly to human health concerns arising from chronic exposure to pyrrolizidine alkaloids and mycotoxins. This study aimed to simultaneously determine 79 natural contaminants, including mycotoxins, as well as pyrrolizidine and tropane alkaloids in herbal dietary supplements in one analytical run. Exposure assessment and human health risks were assessed for all compounds included in this study. The total concentration of naturally occurring contaminants in herbal dietary supplements reached 5.3 mg kg and the most frequently detected mycotoxins were tentoxin and alternariol monomethyl ether. The latter was detected with the highest frequency, reaching concentrations up to 2.5 mg kg. The obtained results indicate a potential risk to public health related to herbal dietary supplement consumption.
草药膳食补充剂的市场需求正在迅速增长，此类产品对消费者来说越来越普遍和容易获得。然而，关于它们安全性的知识仍然不完整。草药膳食补充剂是可能对人类健康造成慢性暴露于吡咯里西啶生物碱和霉菌毒素的关注的食物组之一。本研究旨在同时测定 79 种天然污染物，包括霉菌毒素以及吡咯里西啶和托烷生物碱在草药膳食补充剂中的含量。对本研究中包含的所有化合物进行了暴露评估和人类健康风险评估。草药膳食补充剂中天然污染物的总浓度达到 5.3mg/kg，最常检测到的霉菌毒素是 tentoxin 和 alternariol monomethyl ether。后者的检测频率最高，浓度高达 2.5mg/kg。所得结果表明与草药膳食补充剂消费相关的公共健康存在潜在风险。
