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主动脉内球囊反搏在二尖瓣手术中的临床影响。

Clinical Impact of the Endo-aortic Clamp for Redo Mitral Valve Surgery.

机构信息

Division of Cardiac Surgery, Cardiovascular and Thoracic Department, Città Della Salute E Della Scienza, University Hospital of Turin, Corso Bramante 88, 10126, Turin, Italy.

Department of Anesthesia and Critical Care, Città Della Salute E Della Scienza, University Hospital of Turin, Turin, Italy.

出版信息

J Cardiovasc Transl Res. 2024 Oct;17(5):1011-1017. doi: 10.1007/s12265-024-10509-7. Epub 2024 Apr 17.

Abstract

Aim of this study was to compare redo MV surgery patients undergoing right mini-thoracotomy and EAC with redo MV patients undergoing surgery through other approaches. Redo MV patients from 7 European centers were analyzed. Primary endpoint was 30-day mortality; secondary endpoints were stroke, re-exploration, low cardiac output syndrome (LCOS), respiratory failure, and intensive care unit (ICU) and in-hospital length-of-stay. Forty-nine patients underwent right mini-thoracotomy and EAC (22.7%), and 167 (77.3%) underwent surgery through other approaches (112 sternotomy, 40 unclamped mini-thoracotomies, and 15 mini-thoracotomies with trans-thoracic clamp). Thirty-day mortality, stroke, re-exploration for bleeding, and weaning failure were comparable. The EAC group showed significant lower rate of LCOS (p = 0.03) and shorter ICU (p = 0.04) and in-hospital length of stay (p = 0.002). The EAC allows the surgeon to reach the aorta, to clamp it, and to deliver the cardioplegia with a "no-touch" technique, with significant improvement in outcomes.

摘要

本研究旨在比较经右小开胸和体外循环(EAC)行二尖瓣再次手术的患者与经其他途径行二尖瓣再次手术的患者。分析了来自 7 个欧洲中心的二尖瓣再次手术患者。主要终点为 30 天死亡率;次要终点为卒中、再次探查、低心输出量综合征(LCOS)、呼吸衰竭以及重症监护病房(ICU)和住院时间。49 例患者行右小开胸和 EAC(22.7%),167 例患者行其他途径手术(112 例胸骨切开术、40 例非钳闭小开胸术和 15 例经胸钳闭小开胸术)。30 天死亡率、卒中和出血再次探查以及撤机失败率相似。EAC 组的 LCOS 发生率显著较低(p=0.03),ICU(p=0.04)和住院时间(p=0.002)显著缩短。EAC 允许外科医生触及主动脉,对其进行钳夹,并采用“无接触”技术递送心脏停搏液,从而显著改善了结果。

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