纤连蛋白基因的重复模块化结构：与蛋白质结构及亚基变异的关系。
Repeating modular structure of the fibronectin gene: relationship to protein structure and subunit variation.
作者信息
Odermatt E, Tamkun J W, Hynes R O
出版信息
Proc Natl Acad Sci U S A. 1985 Oct;82(19):6571-5. doi: 10.1073/pnas.82.19.6571.
Abstract
Analysis of the exon-intron structure of the rat fibronectin gene shows that exons correspond precisely with repeating structural units in the protein and that alternative use of some exons produces fibronectin subunits that differ by the presence or absence of certain structural modules. Secondary structure predictions suggest that the repeating structure of the protein is further subdivided into smaller structural units and that these also correspond with exons in the gene.
摘要
对大鼠纤连蛋白基因外显子-内含子结构的分析表明，外显子与蛋白质中的重复结构单元精确对应，并且某些外显子的交替使用产生了因某些结构模块的存在或缺失而不同的纤连蛋白亚基。二级结构预测表明，该蛋白质的重复结构进一步细分为更小的结构单元，并且这些单元也与基因中的外显子相对应。
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Proc Natl Acad Sci U S A. 1985 Oct;82(19):6571-5. doi: 10.1073/pnas.82.19.6571.
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