Petrova Svetlana Lukáš, Pavlova Ewa, Pokorný Václav, Sincari Vladimir
Institute of Macromolecular Chemistry v.v.i., Academy of Sciences of the Czech Republic Heyrovsky Sq. 2 162 06 Prague 6 Czech Republic
Nanoscale Adv. 2024 Mar 11;6(8):1992-1996. doi: 10.1039/d3na01038d. eCollection 2024 Apr 16.
Successful generation of micelles, vesicles, and/or worms with controllable sizes was achieved through the self-assembly process of the poly[-(2-hydroxypropyl)]methacrylamide--polylactide (PHPMAA--PLA) graft copolymer within a microfluidic channel. A product diagram was created to illustrate various morphologies associated with different polymer concentrations, all while maintaining a constant flow velocity ratio between water and the polymer solution.
通过聚[-(2-羟丙基)]甲基丙烯酰胺-聚丙交酯(PHPMAA-PLA)接枝共聚物在微流控通道内的自组装过程,成功生成了尺寸可控的胶束、囊泡和/或蠕虫状结构。绘制了一个产物示意图,以说明与不同聚合物浓度相关的各种形态,同时保持水和聚合物溶液之间恒定的流速比。