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体外冲击波碎石术:过早失宠?来自澳大利亚一家高手术量中心的7年回顾性研究。

Extracorporeal shock wave lithotripsy: Prematurely falling out of favour? A 7 year retrospective study from an Australian high-volume centre.

作者信息

Patel Nishal, Stephenson-Smith Brittany, Roberts Jay, Kothari Akshay

机构信息

Department of Urology The Prince Charles Hospital Brisbane Queensland Australia.

Faculty of Medicine The University of Queensland Brisbane Queensland Australia.

出版信息

BJUI Compass. 2023 Dec 2;5(4):460-465. doi: 10.1002/bco2.314. eCollection 2024 Apr.

Abstract

OBJECTIVES

The aim of this study is to audit 7 years of data with a 3 year follow up from a high-volume stone centre performing extracorporeal shock wave lithotripsy (ESWL) to evaluate efficacy in stone clearance compared to existing knowledge and understand reasons for this performance.

METHODS

Patients who received ESWL treatment for renal or proximal ureteric stones at a single centre between January 2012 and January 2019 (to allow minimum 3 year follow up) were retrieved. A retrospective analysis was performed cross referencing for stone size, location, treatment and need for further procedures. Ethical approval was granted through Metro North HHS HREC, Queensland, Australia.

RESULTS

A total of 1930 patients met inclusion criteria. Fifty-seven percent ( = 1100) underwent left-sided ESWL, compared to 43% ( = 830) on the right. Stone size and location were both statistically significant to treatment outcome. Small stones (<1 cm) had an overall clearance rate of 81.9%, medium stones (1-2 cm) had a clearance rate of 60.6% and stones (>2 cm) had a clearance rate of 31.3%. Small stones in an upper calyx had the highest clearance rate (87.5%,  = 120). Allowing for two procedures, 89% of stones were treated successfully.

CONCLUSION

ESWL remains a legitimate option for the treatment of small and medium sized renal calculi. ESWL stone clearance rates at our centre are higher than published elsewhere and serve as proof to its efficacy. X-ray imaging on the day of the procedure, heavy consultant input and frequent intra-operative imaging are cited as key reasons for success. Further research is warranted to elucidate factors affecting stone clearance rate and to enable more standardised outcomes. Further investment may be required into ESWL provisions in most Australian states and especially in Queensland to enable its continued use in contrast to developing endourological techniques.

摘要

目的

本研究旨在审核一家进行体外冲击波碎石术(ESWL)的大型结石中心7年的数据,并进行3年随访,以评估结石清除效果,并与现有知识进行比较,同时了解取得该效果的原因。

方法

检索2012年1月至2019年1月期间在单一中心接受ESWL治疗肾或输尿管上段结石的患者(以确保至少3年的随访)。进行回顾性分析,交叉参考结石大小、位置、治疗情况以及进一步治疗的需求。经澳大利亚昆士兰州北梅特罗健康与医院服务部人类研究伦理委员会批准。

结果

共有1930名患者符合纳入标准。57%(n = 1100)接受了左侧ESWL治疗,右侧为43%(n = 8)。结石大小和位置对治疗结果均有统计学意义。小结石(<1 cm)的总体清除率为81.9%,中等大小结石(1 - 2 cm)的清除率为60.6%,大结石(>2 cm)的清除率为31.3%。上盏小结石的清除率最高(87.5%,n = 120)。允许进行两次治疗,89%的结石得到成功治疗。

结论

ESWL仍然是治疗中小型肾结石的合理选择。我们中心的ESWL结石清除率高于其他地方公布的数据,证明了其有效性。术中当天的X线成像、专家的大量参与以及频繁的术中成像被认为是成功的关键因素。有必要进一步研究以阐明影响结石清除率的因素,并实现更标准化的结果。与发展中的腔内泌尿外科技术相比,澳大利亚大多数州,尤其是昆士兰州,可能需要进一步投资于ESWL设备,以使其能够继续使用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/723a/11019251/272062360f6d/BCO2-5-460-g001.jpg

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