Gul Amresh, Khan Zahid
General Practice, Lifeline Hospital, Salalah, OMN.
Acute Medicine, Mid and South Essex NHS Foundation Trust, Southend on Sea, GBR.
Cureus. 2024 Mar 18;16(3):e56366. doi: 10.7759/cureus.56366. eCollection 2024 Mar.
Osteosarcoma is a malignant mesenchymal tumour. This primarily manifests in the formation of immature osteoid cells by tumour cells. Osteosarcoma is the most common primary bone tumour in children and adolescents. It tends to occur in the metaphysis of long shafts, shows osteoblastic differentiation, and produces malignant osteoid material. We present the case of a 17-year-old male who presented to our clinic who had left knee pain for a few days. An initial radiograph of the knee joint revealed a lytic lesion in the proximal tibia and further imaging was advised. During a follow-up visit, the patient had worsening pain and had a computerized tomography scan of the left knee, confirming osteosarcoma on the lateral side of the left tibia. He was referred to the orthopaedic department, where a biopsy was performed, to confirm the diagnosis of osteosarcoma. The patient was commenced on chemotherapy due to metastatic disease and has so far tolerated therapy well.
骨肉瘤是一种恶性间充质肿瘤。其主要表现为肿瘤细胞形成不成熟的类骨质细胞。骨肉瘤是儿童和青少年中最常见的原发性骨肿瘤。它倾向于发生在长骨干骺端，表现为成骨细胞分化，并产生恶性类骨质物质。我们报告一例17岁男性病例，该患者因左膝疼痛数天前来我院就诊。膝关节的初步X线片显示胫骨近端有溶骨性病变，建议进一步进行影像学检查。在随访过程中，患者疼痛加重，对左膝进行了计算机断层扫描，证实左胫骨外侧为骨肉瘤。他被转诊至骨科，在那里进行了活检，以确诊骨肉瘤。由于存在转移性疾病，该患者开始接受化疗，到目前为止对治疗耐受性良好。
