Department of Health Behavior and Biological Sciences, University of Michigan School of Nursing, Ann Arbor, Michigan, USA.
School of Nursing, University of Michigan, Ann Arbor, Michigan, USA.
J Adolesc Young Adult Oncol. 2024 Aug;13(4):665-673. doi: 10.1089/jayao.2024.0053. Epub 2024 Apr 18.
Few studies have specifically targeted symptom management interventions for adolescent and young adult (AYA) cancer survivors. A greater understanding of AYA cancer survivors' experiences with cancer treatment-related symptoms would help develop age-appropriate oncology symptom management interventions. The purpose of this qualitative analysis was to explore AYA cancer survivors' experience with cancer treatment-related symptoms. Nineteen post-treatment AYA cancer survivors (18-39 years old) who self-reported moderate-severe cancer treatment-related symptom severity participated in video conferencing or telephone interviews. The questions in the interview guide queried participants to share their experience with cancer treatment-related symptoms. Inductive content analysis was used to identify themes from the interviews. The themes that emerged from the interviews included (1) cancer treatment-related symptoms negatively affected AYA cancer survivors' quality of life (e.g., symptoms served as a reminder of cancer recurrence possibility); (2) AYA cancer survivors' attitudes and feelings about communicating cancer treatment-related symptom concerns to clinicians (e.g., patient-clinician communication was bolstered when AYAs perceived that symptoms were being taken seriously); (3) AYA cancer survivors are interested in oncology symptom management clinical trials, but logistical challenges are barriers to participation; and (4) AYA cancer survivors are interested in nonpharmacological treatments for symptom management. Results highlight the burden of cancer treatment-related symptoms on day-to-day life among post-treatment AYA cancer survivors. Future work is needed to identify nonpharmacological symptom management interventions, strategies to improve patient-clinician communication about symptoms, and strategies to increase the visibility and accessibility of symptom management clinical trials for AYA cancer survivors.
很少有研究专门针对青少年和年轻成人（AYA）癌症幸存者的症状管理干预措施。更深入地了解 AYA 癌症幸存者在癌症治疗相关症状方面的经历，将有助于制定适合年龄的肿瘤症状管理干预措施。本定性分析的目的是探讨 AYA 癌症幸存者在癌症治疗相关症状方面的经历。19 名接受过治疗的 AYA 癌症幸存者（18-39 岁）自我报告有中度至重度癌症治疗相关症状的严重程度，他们参加了视频会议或电话访谈。访谈指南中的问题询问了参与者分享他们与癌症治疗相关症状的经历。采用归纳内容分析法从访谈中确定主题。访谈中出现的主题包括：（1）癌症治疗相关症状对 AYA 癌症幸存者的生活质量产生负面影响（例如，症状提醒癌症复发的可能性）；（2）AYA 癌症幸存者对与临床医生沟通癌症治疗相关症状的态度和感受（例如，当 AYA 认为症状得到认真对待时，患者-临床医生的沟通就会得到加强）；（3）AYA 癌症幸存者对肿瘤症状管理临床试验感兴趣，但参加临床试验的实际困难是阻碍；（4）AYA 癌症幸存者对症状管理的非药物治疗感兴趣。研究结果突出了癌症治疗相关症状对治疗后 AYA 癌症幸存者日常生活的负担。需要进一步的研究来确定非药物症状管理干预措施、改善患者与临床医生之间症状沟通的策略，以及提高 AYA 癌症幸存者对症状管理临床试验的可见性和可及性的策略。
