Boyer William R, Brenton Madison, Ehrlich Samantha F, Churilla James R, Fitzhugh Eugene C
Department of Kinesiology, California Baptist University, Riverside, California, USA.
Department of Public Health, University of Tennessee Knoxville, Knoxville, Tennessee, USA.
Metab Syndr Relat Disord. 2024 Aug;22(6):422-427. doi: 10.1089/met.2023.0041. Epub 2024 Apr 17.
Previous studies have indicated an inverse relationship between aerobic physical activity (PA) and risk of diabetes-related mortality (DRM). However, the contribution of aerobic PA across multiple domains, while also considering the contribution of muscle-strengthening activity (MSA), in reduction of risk for DRM has yet to be examined. The aim of this study is to examine the individual and combined associations of aerobic PA and MSA with DRM. The study sample ( = 13,350) included adult (20-79 years of age) participants from the 1999 to 2006 National Health and Nutrition Examination Survey. PA was categorized into 6 categories based around the 2018 PA guidelines: category 1 (inactive), category 2 (insufficient aerobic PA and no MSA), category 3 [active (aerobic) and no MSA], category 4 (no aerobic PA and sufficient MSA), category 5 (insufficient aerobic PA and sufficient MSA), and category 6 (meeting both recommendations). The dependent variable in this study was DRM, which includes those who had diabetes as the primary cause of death as well as those with diabetes listed as an underlying cause of death. Cox proportional hazards models were used for all analyses. Following adjustment for covariates, significant risk reductions for DRM were found only in category 3 (HR = 0.57; 95% confidence interval: 0.37-0.88). Results suggest that meeting the aerobic PA guidelines significantly reduces the risk for DRM. Those meeting versus not meeting the MSA guidelines seem to have no difference in risk for DRM independent of aerobic PA.
先前的研究表明，有氧体育活动（PA）与糖尿病相关死亡率（DRM）风险之间存在负相关关系。然而，有氧PA在多个领域的贡献，同时考虑肌肉强化活动（MSA）在降低DRM风险方面的贡献，尚未得到研究。本研究的目的是检验有氧PA和MSA与DRM的个体及联合关联。研究样本（n = 13350）包括来自1999年至2006年国家健康和营养检查调查的成年（20 - 79岁）参与者。根据2018年PA指南，PA被分为6类：第1类（不活动），第2类（有氧PA不足且无MSA），第3类[活跃（有氧）且无MSA]，第4类（无氧PA且MSA充足），第5类（有氧PA不足且MSA充足），以及第6类（符合两项建议）。本研究的因变量是DRM，包括那些以糖尿病为主要死亡原因以及那些将糖尿病列为潜在死亡原因的人。所有分析均使用Cox比例风险模型。在对协变量进行调整后，仅在第3类中发现DRM风险显著降低（HR = 0.57；95%置信区间：0.37 - 0.88）。结果表明，符合有氧PA指南可显著降低DRM风险。无论有氧PA如何，符合与不符合MSA指南的人在DRM风险方面似乎没有差异。
