Beller F K, Dame W R, Ebert C
Aust N Z J Obstet Gynaecol. 1985 May;25(2):83-6. doi: 10.1111/j.1479-828x.1985.tb00613.x.
Twelve patients are presented with the symptomatology of haemolysis, elevated liver enzymes and low platelet count (HELLP syndrome). Only 3 patients experienced a progressive course; the rest did not differ from a group of 130 patients suffering from severe preeclampsia. There was no significant difference in the concentration of plasma fibrinogen, fibrinogen monomer complex and antithrombin III. Two patients were treated with heparin without improvement of the coagulation data or the severity of the disease. The subgrouping of very severe preeclampsia may be desirable, but it is felt that this group is insufficiently characterized by the symptomatology of HELLP. The evaluation of better criteria may allow identification of subgroups of preeclamptic patients with severe prognostic criteria.
本文报告了12例出现溶血、肝酶升高和血小板计数降低症状（HELLP综合征）的患者。只有3例患者病情呈进行性发展；其余患者与130例重度子痫前期患者无异。血浆纤维蛋白原、纤维蛋白原单体复合物和抗凝血酶III的浓度无显著差异。2例患者接受肝素治疗，但凝血数据和疾病严重程度均未改善。对极重度子痫前期进行亚组分类可能是可取的，但认为该组患者的HELLP症状特征并不充分。评估更好的标准可能有助于识别出具有严重预后标准的子痫前期患者亚组。
