Nursing and Midwifery Care Research Center, Isfahan University of Medical Sciences, Isfahan, Iran.
Based Psychiatric Care Research Center, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Iran.
Epilepsy Behav. 2024 Jun;155:109776. doi: 10.1016/j.yebeh.2024.109776. Epub 2024 Apr 17.
Medication adherence is of utmost importance in achieving the desired therapeutic outcome and effectively managing seizures in patients with epilepsy (PWE). It is imperative to recognize self-esteem as a psychological determinant that potentially influences the optimal compliance with anti-seizure medications (ASMs) among PWE. The objective of this study was to explore medication adherence and its relationship with self-esteem among individuals diagnosed with epilepsy in Isfahan, Iran.
This descriptive-analytical study was conducted in the year 2021, encompassing a cohort of 250 PWE who were referred to designated medical facilities in Isfahan, Iran, and were selected by the consecutive sampling technique. A 3-part instrument including demographic components, the Rosenberg Self-Esteem Scale, and the Morissky Drug Adherence Questionnaire employed for data collection.
The mean and standard deviation of adherence to the medicinal regimen in the participants were 6.9 ± 2.02, and 46.4 % had a low level of adherence to the medication regimen (total score 0-6). At the same time, the mean and standard deviation of self-esteem in these patients was 5.11 ± 2.11. There was a statistically significant and direct correlation between adherence to the prescribed drug regimen and self-esteem (rs = 0.464, p = 0.00).
Based on the findings of the study that showed a statistically significant and positive correlation between self-esteem and adherence to the medication regimen, it is advisable to enhance and advocate for these factors in PWE.
在实现理想的治疗效果和有效控制癫痫患者（PWE）的癫痫发作方面，药物依从性至关重要。必须认识到自尊是一种心理决定因素，它可能会影响 PWE 对抗癫痫药物（ASMs）的最佳依从性。本研究的目的是探讨伊朗伊斯法罕癫痫患者的药物依从性及其与自尊的关系。
这是一项描述性分析研究，于 2021 年进行，包括 250 名被转诊到伊朗伊斯法罕指定医疗机构的 PWE 患者，采用连续抽样技术进行选择。采用包括人口统计学部分、罗森伯格自尊量表和莫瑞斯基药物依从性问卷在内的 3 部分工具进行数据收集。
参与者对药物治疗方案的依从性平均得分为 6.9±2.02，46.4%的患者对药物治疗方案的依从性较低（总分为 0-6）。与此同时，这些患者的自尊平均得分为 5.11±2.11。药物治疗方案的依从性与自尊之间存在显著的直接相关性（rs=0.464，p=0.00）。
基于研究结果表明，自尊与药物治疗方案的依从性之间存在显著的正相关关系，建议在 PWE 中增强和倡导这些因素。
