Department of Gastroenterology, The First People's Hospital of Shizuishan, Affiliated to Ningxia Medical University, Shizuishan, China.
Department of Pathology, The First People's Hospital of Shizuishan, Affiliated to Ningxia Medical University, Shizuishan, China.
Medicine (Baltimore). 2024 Apr 19;103(16):e37877. doi: 10.1097/MD.0000000000037877.
Inflammatory fibroid polyp (IFP), also known as Vanek tumor, is a rare, benign gastrointestinal lesion characterized by its inflammatory and fibroid histological features. IFP is often discovered incidentally during endoscopic examinations. It is exceedingly rare for an IFP to prolapse into the duodenum and results in incomplete obstruction of the pylorus.
A 64-year-old male patient was admitted to the hospital with recurrent episodes of melena over a 6-month period, along with complaints of dizziness and fatigue in the past 10 days.
Gastroscopy showed a giant polypoid mass on the posterior wall of the gastric antrum, prolapsing into the duodenum. Abdominal computer tomography (CT) confirmed the tumor protruding into the duodenum. Pathologic examination of the resected specimen confirmed the IFP diagnosis.
The giant tumor was completely and successfully excised using endoscopic submucosal dissection (ESD). After the surgery, the patient underwent acid suppression and fluid replenishment therapy.
The patient responded well to ESD and was discharged in stable condition. As of the submission of the case report, there has been no recurrence of the tumor after a 5-month follow-up, and the patient is still under follow-up.
While IFPs have traditionally been managed surgically, ESD demonstrates promising treatment outcomes, avoiding the need for surgical distal gastrectomy, and emerges as a safe and effective treatment option.
炎性纤维息肉（IFP），又称 Vanek 瘤，是一种罕见的良性胃肠道病变，其组织学特征为炎症和纤维瘤性。IFP 常在内镜检查中偶然发现。IFP 很少脱垂入十二指肠并导致幽门不完全梗阻。
一名 64 岁男性患者因反复黑便 6 个月，伴头晕、乏力 10 天入院。
胃镜检查显示胃窦后壁有一巨大息肉样肿块，向十二指肠内脱垂。腹部计算机断层扫描（CT）证实肿瘤向十二指肠突出。切除标本的病理检查证实了 IFP 的诊断。
使用内镜黏膜下剥离术（ESD）完全切除巨大肿瘤。术后，患者接受抑酸和补液治疗。
患者对 ESD 反应良好，病情稳定出院。截至病例报告提交时，患者在 5 个月的随访中未再复发肿瘤，仍在随访中。
虽然 IFP 传统上采用手术治疗，但 ESD 显示出有前景的治疗效果，避免了远端胃切除术，是一种安全有效的治疗选择。
