Division of Plastic and Reconstructive Surgery, Department of Surgery, National Cheng Kung University, Tainan, Taiwan.
Department of Occupational Therapy, College of Medicine, National Cheng Kung University, Tainan, Taiwan.
Medicine (Baltimore). 2024 Apr 19;103(16):e37868. doi: 10.1097/MD.0000000000037868.
The conventional treatment of giant cell tumors is intralesional curettage with local adjuvant therapy. Because hand tumors have a high local recurrence, the primary goal for treating tumors of the hand is to eradicate the lesion.
To preserve the metacarpophalangeal (MCP) joint function as well as avoid further recurrence after surgery.
The giant cell tumor invades the patient's MCP joint in an index proximal phalanx.
Using computer-aided design and three-dimensional printing techniques, we reformed the original shapes of the MCP joint and its peripheral bone to replica models. The surgeon then performed an en bloc resection and proximal phalanx with MCP joint reconstruction by fabricating the patient's costal osteochondral graft during the operation.
After 6 months of rehabilitation, the patient's finger functions could pinch and grasp objects naturally. At the 1-year follow-up, the range of motion of the MCP, proximal interphalangeal, and distal interphalangeal joints improved from flexion of 35° to 60°, 75° to 85°, and 60° to 80°, respectively. The hand function achieved the mean performance of non-preferred hands for young females at the postoperative 3-year follow-up.
The customized prototyping technique has the potential to replica the original patient's bony graft to reach the goal of minimizing the defects at the donor site and maximizing the function of the reconstructed MCP joint.
对于骨巨细胞瘤,传统的治疗方法是病灶内切除术联合局部辅助治疗。由于手部肿瘤局部复发率较高,手部肿瘤的主要治疗目标是彻底清除病灶。
既要保留掌指(MCP)关节的功能,又要避免术后进一步复发。
巨细胞瘤侵犯患者食指近节指骨的 MCP 关节。
我们应用计算机辅助设计和三维打印技术,对 MCP 关节及其周围骨骼的原始形状进行了改造,制作出模型。然后,外科医生在手术中使用患者肋软骨骨软骨移植进行整块切除和 MCP 关节重建。
康复 6 个月后,患者手指的捏握功能自然。在 1 年的随访中,MCP、近侧指间关节和远侧指间关节的活动度分别从屈曲 35°改善至 60°、75°改善至 85°和 60°改善至 80°。术后 3 年的随访时,手部功能达到年轻女性非优势手的平均表现。
定制原型技术有可能复制患者原始骨移植物,从而达到最大限度减少供体部位缺陷和最大限度提高重建 MCP 关节功能的目的。