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双角双胎妊娠在双角双子宫中的围产期管理:病例报告及文献复习。

Peripartal management of dichorial twin pregnancy in a bicornuate bicollis uterus: a case report and review of the literature.

机构信息

Department of Obstetrics and Gynecology, University Hospital of Schleswig Holstein, Campus Kiel, 24105, Kiel, Germany.

Department of Obstetrics and Gynecology, University Hospital of Würzburg, 97080, Würzburg, Germany.

出版信息

J Med Case Rep. 2024 Apr 21;18(1):196. doi: 10.1186/s13256-024-04506-2.

Abstract

INTRODUCTION

The management of a pregnancy in a bicornuate uterus is particularly challenging. A bicornuate uterus is a rare occurrence and a twin pregnancy in a bicornuate uterus even more rare. These pregnancies call for intensive diagnostic investigation and interdisciplinary care.

CASE PRESENTATION

We report on a 27-year-old European woman patient (gravida I, para 0) with a simultaneous pregnancy in each cavity of a bicornuate bicollis uterus after embryo transfer. The condition was confirmed by hysteroscopy and laparoscopy. Several unsuccessful in vitro fertilization (IVF) attempts had been performed earlier before embryo transfer in each cornus. After a physiological course of pregnancy with differential screening at 12 + 6 weeks and 22 + 0 weeks of gestation, the patient presented with therapy-resistant contractions at 27 + 2 weeks. This culminated in the uncomplicated spontaneous delivery of the leading fetus and delayed spontaneous delivery of the second fetus.

DISCUSSION

Only 16 cases of twin pregnancy in a bicornuate unicollis uterus have been reported worldwide and only 6 in a bicornuate bicollis uterus. The principal risks in such pregnancies are preterm labor, intrauterine growth restriction, malpresentation and preeclampsia. These typical risk factors of a twin pregnancy are greatly potentiated in the above mentioned setting.

CONCLUSION

A twin pregnancy in the presence of a uterine malformation is rare and difficult to manage. These rare cases must be collected and reported in order to work out algorithms of monitoring and therapy as well as issue appropriate recommendations for their management.

摘要

介绍

双角子宫妊娠的管理极具挑战性。双角子宫较为罕见,而双角子宫内的双胎妊娠更为罕见。这些妊娠需要进行强化诊断检查和跨学科护理。

病例介绍

我们报告了一例 27 岁的欧洲女性患者(初产妇,0 产次),在胚胎移植后,她的双角双子宫的每个宫腔内均出现了妊娠。该情况通过宫腔镜和腹腔镜得到了确诊。在此之前,患者曾进行了多次体外受精(IVF)尝试,但均未成功,每次均在每个角内进行胚胎移植。妊娠过程正常,在妊娠 12+6 周和 22+0 周进行了差异筛查后,患者在 27+2 周时出现了治疗抵抗性宫缩。这最终导致了主导胎儿的自然分娩和第二胎儿的延迟自然分娩。

讨论

全球仅报告了 16 例双角单子宫内的双胎妊娠,而双角双子宫内的仅 6 例。此类妊娠的主要风险是早产、宫内生长受限、胎位不正和子痫前期。这些双胎妊娠的典型风险因素在上述情况下大大加剧。

结论

存在子宫畸形的双胎妊娠罕见且难以管理。这些罕见病例必须收集和报告,以便制定出监测和治疗的方案,并为其管理提出适当的建议。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb7c/11032606/681f0d98448c/13256_2024_4506_Fig1_HTML.jpg

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