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哺乳动物鼻腔中的空调取决于它们的质量和最大奔跑速度。

The air conditioning in the nose of mammals depends on their mass and on their maximal running speed.

机构信息

TIPs (Transfers, Interfaces and Processes), Université libre de Bruxelles, 1050, Brussels, Belgium.

Laboratoire de Pharmacie galénique et de Biopharmacie, Université libre de Bruxelles, 1050, Brussels, Belgium.

出版信息

Sci Rep. 2024 Apr 20;14(1):9053. doi: 10.1038/s41598-024-59768-z.

Abstract

The nose of the mammals is responsible for filtering, humidifying, and heating the air before entering the lower respiratory tract. This conditioning avoids, notably, dehydration of the bronchial and alveolar mucosa. However, since this conditioning is not perfect, exercising in cold air can induce lung inflammation, both for human and non-human mammals. This work aims to compare the air conditioning in the noses of various mammals during inspiration. We build our study on computational fluid dynamics simulations of the heat exchanges in the lumen of the upper respiratory tract of these mammals. These simulations show that the efficiency of the air conditioning in the nose during inspiration does not relate only to the mass m of the mammal but also to its maximal running speed v. More precisely, the results allow establishing a scaling law relating the efficiency of air conditioning in the nose of mammals to the ratio . The simulations also correlate the resistance to the flow in the nose to the efficiency of this air conditioning. The obtained scaling law allows predicting the air temperature at the top of the trachea during inspiration for nasal-breathing mammals, and thus notably for humans of various ages.

摘要

哺乳动物的鼻子负责在进入下呼吸道之前过滤、加湿和加热空气。这种调节作用避免了支气管和肺泡黏膜的显著脱水。然而,由于这种调节并不完美,在冷空气下运动可能会导致肺部炎症,无论是人类还是非人类哺乳动物都会发生。本工作旨在比较各种哺乳动物在吸气过程中鼻子的空气调节功能。我们的研究基于对这些哺乳动物上呼吸道腔体内热量交换的计算流体动力学模拟。这些模拟表明,吸气过程中鼻子的空气调节效率不仅与哺乳动物的质量 m 有关,还与哺乳动物的最大奔跑速度 v 有关。更准确地说,结果建立了一个将哺乳动物鼻子空气调节效率与比率 的关系的标度律。模拟还将鼻腔内的流动阻力与空气调节效率相关联。所得到的标度律允许预测在鼻呼吸哺乳动物吸气过程中气管顶部的空气温度,因此也可以预测不同年龄的人类的空气温度。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d3d7/11032399/1eb6452f22ad/41598_2024_59768_Fig1_HTML.jpg

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