School of Medicine, Westchester Medical Center, New York Medical College, 40 Sunshine Cottage Rd, Valhalla, NY, 10595, USA.
College of Osteopathic Medicine, New York Institute of Technology, Glen Head, NY, USA.
Eur J Orthop Surg Traumatol. 2024 Jul;34(5):2465-2471. doi: 10.1007/s00590-024-03941-7. Epub 2024 Apr 20.
To assess the utility of frailty in predicting outcomes following surgical intervention for KDs.
The NIS database was queried for non-congenital knee dislocations from 2015 to 2019 that underwent ligament repair or surgical reduction. Patients were assigned frailty scores using the mFI-11, and outcomes were compared. Multivariate regression and ROC curve analysis were used to assess the independent association of obesity, frailty, VI, and age with adverse outcomes.
A total of 3797 patients who underwent surgical management were included. Frailty was associated with extended LOS (OR 1.353, 95% CI 1.212-1.510, p < 0.001), adverse discharge (OR 1.716, 95% CI 1.515-1.946, p < 0.001), and complications (OR 1.449, 95% CI 1.352-1.553, p < 0.001). Severely frailty was associated with extended LOS (OR 1.838, 95% CI 1.611-2.097, p < 0.001), adverse discharge (OR 2.756, 95% CI 2.394-3.171, p < 0.001), and complications (OR 1.603, 95% CI 1.453-1.768, p < 0.001). Additionally, VI was a risk factor for extended LOS (OR 7.647 (6.442-9.076) p < 0.001), complications (OR 2.065 (1.810-2.341) p < 0.001), and adverse discharge (OR 1.825 (1.606-2.075), p < 0.001). Obesity was a risk factor for extended LOS (OR 1.599 (1.470-1.739), p < 0.001) and complications (OR 1.235 (1.108-1.377), p < 0.001). AUC analysis showed that frailty was the most accurate predictor of all outcomes when compared to VI, obesity, and age.
Frailty is superior to age and obesity, and comparable to VI, at predicting adverse outcomes following surgical management of KDs. These findings suggest that frailty assessment might play a role in risk stratification and preoperative planning for KD patients that require surgical intervention.
评估虚弱程度在预测 KD 手术干预后结局中的作用。
从 2015 年至 2019 年,对 NIS 数据库中接受韧带修复或手术复位的非先天性膝关节脱位患者进行查询。使用 mFI-11 为患者分配虚弱评分,并比较结果。使用多变量回归和 ROC 曲线分析评估肥胖、虚弱、VI 和年龄与不良结局的独立关联。
共纳入 3797 例接受手术治疗的患者。虚弱与 LOS 延长(OR 1.353,95%CI 1.212-1.510,p<0.001)、不良出院(OR 1.716,95%CI 1.515-1.946,p<0.001)和并发症(OR 1.449,95%CI 1.352-1.553,p<0.001)相关。严重虚弱与 LOS 延长(OR 1.838,95%CI 1.611-2.097,p<0.001)、不良出院(OR 2.756,95%CI 2.394-3.171,p<0.001)和并发症(OR 1.603,95%CI 1.453-1.768,p<0.001)相关。此外,VI 是 LOS 延长(OR 7.647(6.442-9.076)p<0.001)、并发症(OR 2.065(1.810-2.341)p<0.001)和不良出院(OR 1.825(1.606-2.075)p<0.001)的危险因素。肥胖是 LOS 延长(OR 1.599(1.470-1.739)p<0.001)和并发症(OR 1.235(1.108-1.377)p<0.001)的危险因素。AUC 分析表明,与 VI、肥胖和年龄相比,虚弱是预测 KD 手术后不良结局的最准确预测因素。
虚弱程度在预测 KD 手术后的不良结局方面优于年龄和肥胖,与 VI 相当。这些发现表明,虚弱评估可能在 KD 患者需要手术干预的风险分层和术前规划中发挥作用。