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静态间隔物在治疗膝关节复杂假体周围关节感染中起着至关重要的作用。

Static spacers play a crucial role in the treatment of complex periprosthetic joint infections of the knee.

机构信息

Department of Orthopaedics, Heidelberg University Hospital, Heidelberg, Germany.

Center for Orthopedics and Joint Replacement, Marienhaus Hospital St. Wendel-Ottweiler, St. Wendel, Germany.

出版信息

Knee Surg Sports Traumatol Arthrosc. 2024 Jul;32(7):1766-1774. doi: 10.1002/ksa.12187. Epub 2024 Apr 21.

Abstract

PURPOSE

To determine the superior spacer design, a growing number of studies are comparing treatment results between patients having been treated with articulating and static knee spacers in the setting of two-stage revision for periprosthetic joint infection (PJI). In contrast, the primary objective of this study was to compare preoperative characteristics between patients from both spacer groups and examine whether significant differences were present prior to spacer implantation.

METHODS

This retrospective, single-centre, cohort study examined the preoperative situation of 80 consecutive knee PJIs between 2017 and 2020. All patients underwent two-stage revision, with 35 (44%) receiving an articulating and 45 (56%) a static spacer.

RESULTS

No significant differences were observed in terms of patient gender (p = 0.083), age (p = 0.666), comorbidity (p = 0.1) and preoperative clinical function (p = 0.246). Static spacers were significantly more often used in the presence of a periarticular fistula (p = 0.033), infection of a revision implant (p < 0.001), higher degree of bone loss (p < 0.001) and infection caused by a difficult-to-treat pathogen (p = 0.038). Complication and revision rates were similar for both spacer types during the interim period, while patients with articulating spacers demonstrated a superior clinical function (p < 0.001) during the interim period and after reimplantation.

CONCLUSION

Static spacers are being utilised in significantly more complex and unfavourable preoperative scenarios. Therefore, a preoperative selection bias may be at least partially accountable for any disparities observed in postoperative outcomes. To achieve the best possible results, surgeons should know and respect the distinct indications of static and articulating spacers and consequently understand and use them as complementary surgical options.

LEVEL OF EVIDENCE

Level III.

摘要

目的

为了确定最佳的间隔器设计,越来越多的研究比较了在二期翻修治疗假体周围关节感染(PJI)时,使用活动和静态膝关节间隔器治疗的患者之间的治疗结果。相比之下,本研究的主要目的是比较两种间隔器组患者的术前特征,并检查在间隔器植入之前是否存在显著差异。

方法

本回顾性、单中心队列研究检查了 2017 年至 2020 年间 80 例连续膝关节 PJI 患者的术前情况。所有患者均接受二期翻修,其中 35 例(44%)接受活动间隔器,45 例(56%)接受静态间隔器。

结果

在患者性别(p=0.083)、年龄(p=0.666)、合并症(p=0.1)和术前临床功能(p=0.246)方面,两组间无显著差异。在存在关节周围瘘管(p=0.033)、翻修植入物感染(p<0.001)、较高程度的骨质丢失(p<0.001)和由难处理病原体引起的感染时,更常使用静态间隔器。在中期期间,两种间隔器类型的并发症和翻修率相似,而使用活动间隔器的患者在中期和再植入后具有更好的临床功能(p<0.001)。

结论

静态间隔器在术前情况更复杂和不利的情况下更常被使用。因此,术前选择偏倚可能至少部分解释了术后结果观察到的差异。为了获得最佳结果,外科医生应该了解并尊重活动和静态间隔器的不同适应证,并相应地将它们作为互补的手术选择来理解和使用。

证据等级

III 级。

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