Donnan G A, Bladin P F, Woodward J M
Aust N Z J Med. 1985 Jun;15(3):386-91. doi: 10.1111/j.1445-5994.1985.tb04067.x.
Extracranial-intracranial bypass is now a commonly performed procedure in centres with a high level of neurosurgical and vascular expertise. Bypass of surgically inaccessible stenoses or occlusions appears to be a logical technique to prevent future stroke but there is much uncertainty about the clinical indications for surgery and even the natural history of the lesions being bypassed. To answer these questions, the International EC/IC Bypass Study was set up in 1977 with relatively broad entry criteria. The data will be analysed in June 1985 and if the results support the use of bypass as a means of preventing subsequent stroke, the procedure should become firmly established. However, if the results are negative, or inconclusive, rather than discard the procedure, subsets of higher risk patients should be sought, in particular using newer methods of assessing cerebral perfusion and metabolism.
颅外-颅内血管搭桥术目前在具备高水平神经外科和血管专业知识的中心是一种常见的手术。对手术难以触及的狭窄或闭塞进行搭桥似乎是预防未来中风的合理技术，但手术的临床适应症甚至所搭桥病变的自然病史仍存在很多不确定性。为回答这些问题，1977年设立了国际颅外/颅内血管搭桥研究，纳入标准相对宽泛。数据将于1985年6月进行分析，如果结果支持将搭桥作为预防后续中风的手段，该手术应会稳固确立。然而，如果结果为阴性或不确定，不应摒弃该手术，而应寻找更高风险患者亚组，尤其是使用评估脑灌注和代谢的更新方法。
