Department of Valvular Heart Disease, National Institute of Cardiology, Warszawa, Poland.
Clinical Research Support Center, National Institute of Cardiology, Warszawa, Poland.
Kardiol Pol. 2024;82(6):609-616. doi: 10.33963/v.phj.100275. Epub 2024 Apr 22.
Infective endocarditis (IE) is a severe valvular disease associated with high morbidity and mortality.
This preliminary study aimed to evaluate patient profiles and treatment outcomes of IE in Poland and compare them with European IE characteristics.
We conducted a prospective multicenter observational cohort study - the POL-ENDO registry - in IE patients from 134 hospitals in Poland recruited between August 2022 and August 2023. We evaluated demographic, clinical, imaging, and treatment outcome data. A comparison of the Polish patients with those assessed in the EURO-ENDO registry between January 2016 and March 2018 was performed.
Of a total of 880 IE patients, 622 were male (70.7%). The POL-ENDO participants were older (61.4 [16.7] years vs. 59.25 [18.03] years; P = 0.001). Native-valve IE occurred more often in Poland (82.3% vs. 56.6%; P <0.001). Transthoracic echocardiography was performed more frequently in Poland (93.6% vs. 89.8%; P <0.001). New imaging techniques (computed tomography/magnetic resonance imaging/positron emission tomography/single-photon emission computed tomography) were less frequently used in Poland (computed tomography: 41.3% vs. 53.2%; P <0.001; magnetic resonance imaging: 6.4% vs. 18.7%; P <0.001). Heart failure occurred more often in Poland as an in-hospital complication (31.4% vs. 14.1%; P <0.001). Surgical treatment was less frequently performed in Poland (36.9% vs. 51.2%; P <0.001). In-hospital mortality was higher in Poland (21% vs. 17%; P = 0.008).
Polish IE patients were significantly older and had more comorbidities. New imaging techniques are less frequently used in Poland. Echocardiography was performed more frequently in Poland as the diagnostic mainstay. Surgical treatment was significantly less frequent in Poland. In-hospital mortality in Poland is higher.
感染性心内膜炎（IE）是一种严重的瓣膜疾病，与高发病率和死亡率相关。
本初步研究旨在评估波兰 IE 患者的患者特征和治疗结局，并与欧洲 IE 特征进行比较。
我们在 2022 年 8 月至 2023 年 8 月期间，在波兰的 134 家医院中开展了一项前瞻性、多中心观察性队列研究——波兰感染性心内膜炎登记研究（POL-ENDO 登记研究），评估了 IE 患者的人口统计学、临床、影像学和治疗结局数据。对 2016 年 1 月至 2018 年 3 月在 EURO-ENDO 登记研究中评估的波兰患者与其他患者进行了比较。
在总共 880 名 IE 患者中，622 名男性（70.7%）。POL-ENDO 参与者年龄更大（61.4[16.7]岁 vs. 59.25[18.03]岁；P=0.001）。在波兰，原发性瓣膜 IE 更常见（82.3% vs. 56.6%；P<0.001）。波兰更频繁地进行经胸超声心动图检查（93.6% vs. 89.8%；P<0.001）。波兰较少使用新的影像学技术（计算机断层扫描/磁共振成像/正电子发射断层扫描/单光子发射计算机断层扫描）（计算机断层扫描：41.3% vs. 53.2%；P<0.001；磁共振成像：6.4% vs. 18.7%；P<0.001）。波兰更常见住院期间出现心力衰竭作为并发症（31.4% vs. 14.1%；P<0.001）。波兰较少进行手术治疗（36.9% vs. 51.2%；P<0.001）。波兰住院死亡率更高（21% vs. 17%；P=0.008）。
波兰 IE 患者年龄明显更大，合并症更多。波兰较少使用新的影像学技术。波兰更频繁地进行超声心动图检查作为主要诊断方法。波兰手术治疗明显减少。波兰住院死亡率较高。
