Lecklitner M L, Foster R W
Clin Nucl Med. 1985 Sep;10(9):632-4. doi: 10.1097/00003072-198509000-00006.
Diffuse pulmonary uptake by bone-seeking radiopharmaceuticals has been reported previously but, in the same patient, would pulmonary uptake of Ga-67 citrate yield clinically meaningful results? A patient with hypercalcemia and renal failure in whom bone scintigraphy demonstrated striking diffuse bilateral pulmonary uptake, but subsequent gallium imaging demonstrated no evidence of pulmonary uptake greater than body background, is discussed. We conclude that pulmonary uptake of gallium cannot be attributed to calcium deposition and should carry the same clinical significance in regard to inflammatory and malignant lesions as would be assigned to patients without pulmonary calcific deposits.
此前已有关于亲骨性放射性药物在肺部弥漫性摄取的报道，但是，对于同一患者，枸橼酸镓-67的肺部摄取能产生具有临床意义的结果吗？本文讨论了一名高钙血症和肾衰竭患者，其骨闪烁显像显示双侧肺部有明显的弥漫性摄取，但随后的镓显像未发现肺部摄取超过身体本底的证据。我们得出结论，镓的肺部摄取不能归因于钙沉积，对于炎症和恶性病变，其临床意义应与无肺部钙化沉积的患者相同。
