Zandiehvakili Moein, Cui Cathy Kexin, Jeffrey Bronte, Chang Florence Ching-Fen, Emerson Jonathan, Conyngham Samuel
Department of Radiology, Westmead hospital, Sydney, Australia.
Department of Neurology, Westmead hospital, Sydney, Australia.
Radiol Case Rep. 2024 Apr 13;19(7):2613-2616. doi: 10.1016/j.radcr.2024.03.041. eCollection 2024 Jul.
Anti-IgLON5 disease is a rare autoimmune neurological condition which was relatively recently described in the literature. This syndrome encompasses a range of clinical manifestations with most cases showing unremarkable findings on brain magnetic resonance imaging (MRI). Here, we report a case of a 61-year-old female patient with unique brain MRI features that, to the best of our knowledge, has not been reported in the literature before. Following treatment including immunotherapy, the patient experienced significant improvement clinically accompanied by radiological improvement on the follow-up imaging.
抗IgLON5病是一种罕见的自身免疫性神经疾病，在文献中相对较新才被描述。该综合征包括一系列临床表现，大多数病例在脑磁共振成像（MRI）上显示无明显异常。在此，我们报告一例61岁女性患者，其脑MRI具有独特特征，据我们所知，此前文献中尚未有过报道。经过包括免疫治疗在内的治疗后，患者临床症状显著改善，随访影像学检查也显示出放射学上的改善。
