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儿童重症疾病多发性神经病:一例报告

Critical Illness Polyneuropathy in a Child: A Case Report.

作者信息

Chalipat Shiji, Madala Jyothsna Sree, Chavan Sanjay, Malwade Sudhir, Baviskar Shilpa

机构信息

Pediatric Neurology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to Be University), Pune, IND.

Pediatrics, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to Be University), Pune, IND.

出版信息

Cureus. 2024 Mar 22;16(3):e56703. doi: 10.7759/cureus.56703. eCollection 2024 Mar.

Abstract

Critical illness polyneuropathy (CIP) and myopathy (CIM) are underreported conditions in critically ill children with prolonged intensive care unit stays and mechanical ventilation. We report a case of a 10-year-old boy with pneumococcal meningoencephalitis with severe sepsis and multiorgan dysfunction. The child required prolonged ventilation, sedation, and inotropic support. He had repeated extubation failures and the development of quadriparesis with areflexia. Electrophysiology studies were consistent with CIP with acute motor and sensory axonal polyneuropathy and elevated muscle enzymes. He was treated with supportive measures and physiotherapy along with management of the underlying condition. He recovered slowly over 68 days with a good recovery with a modified Rankin's scale score of 4 on discharge. There is a need to pay attention to all critically ill children and should have a high index of suspicion for the development of CIP/CIM which can have an impact on course and outcome.

摘要

危重症多神经病(CIP)和肌病(CIM)在入住重症监护病房时间延长且接受机械通气的危重症儿童中报告不足。我们报告了一例10岁男孩,患有肺炎球菌性脑膜脑炎,伴有严重脓毒症和多器官功能障碍。该患儿需要长时间通气、镇静和使用血管活性药物支持。他多次拔管失败,并出现四肢瘫软伴反射消失。电生理研究结果符合CIP,伴有急性运动和感觉轴索性多神经病,且肌酶升高。对其采取了支持措施、物理治疗以及对基础疾病的治疗。他在68天内缓慢康复,出院时改良Rankin量表评分为4分,恢复良好。有必要关注所有危重症儿童,对于可能影响病程和预后的CIP/CIM的发生应保持高度怀疑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/90ab/11032641/bbe6614b4b23/cureus-0016-00000056703-i01.jpg

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