Gray J A
Scott Med J. 1979 Apr;24(2):141-6. doi: 10.1177/003693307902400208.
The principles of antibacterial prophylaxis and its advantages and disadvantages are reviewed. Controlled trials have shown chemoprophylaxis to be beneficial notably in preventing recurrences of rheumatic carditis and urinary infections and in controlling sepsis after cardiac and hip joint surgery and mid thigh amputations. The recently introduced metronidazole prophylaxis for gastrointestinal and gynaecological operations appears highly effective. The use of prophylaxis is briefly discussed in other situations where its value is less certain or where, in the author's opinion, it is contraindicated.
本文综述了抗菌预防的原则及其优缺点。对照试验表明，化学预防尤其在预防风湿性心脏炎和泌尿系统感染复发，以及控制心脏和髋关节手术及大腿中部截肢术后的败血症方面有益。最近引入的用于胃肠道和妇科手术的甲硝唑预防似乎非常有效。本文还简要讨论了在其他情况下预防措施的使用，这些情况下其价值不太确定，或者在作者看来是禁忌的。
