De Decker A, De Fruyt J
Tijdschr Psychiatr. 2024;66(4):217-220.
In this paper we discuss the case of a 52-year-old man who consulted the emergency department because of confusion. Based on anamnesis, clinical presentation, various technical investigations and recovery after discontinuation of disulfiram, the diagnosis of disulfiram encephalopathy is made. This is a less common but serious complication of a frequently used therapy and underscores the importance of early recognition and careful but also controlled prescription of disulfiram. We describe the pathophysiology behind this complication and reflect on some important numbers.
在本文中，我们讨论了一名52岁男性因意识模糊到急诊科就诊的病例。根据病史、临床表现、各项技术检查以及停用双硫仑后的恢复情况，诊断为双硫仑脑病。这是一种常用治疗方法中不太常见但严重的并发症，强调了早期识别以及谨慎且有控制地开具双硫仑处方的重要性。我们描述了这种并发症背后的病理生理学，并思考了一些重要数据。
