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腹横肌平面阻滞与硬膜外麻醉用于剖宫产术后疼痛管理的初步研究

Transversus Abdominis Plane Block versus Epidural Anesthesia for Pain Management Post-Caesarean Delivery: A Pilot Study.

作者信息

Salazar-Flórez Jorge Emilio, Arenas-Cardona Leidy Tatiana, Marhx Ninemy, López-Guerrero Eduardo, Echeverri-Rendón Ángela Patricia, Giraldo-Cardona Luz Stella

机构信息

Department of Medicine, San Martín University Foundation, Sabaneta, Antioquia, Colombia.

Department of Medicine, Hospital General de Occidente, University Health Sciences Center of University of Guadalajara, Jalisco, Mexico.

出版信息

Local Reg Anesth. 2024 Apr 15;17:39-47. doi: 10.2147/LRA.S444947. eCollection 2024.

Abstract

BACKGROUND

Effective post-operative analgesia profoundly influences patient recovery and outcomes after caesarean delivery. The Transversus Abdominis Plane (TAP) block represents a potential alternative, potentially offering greater effectiveness than epidural analgesia while causing fewer adverse effects.

OBJECTIVE

To assess if the abdominal transverse block provides superior postoperative pain relief in patients undergoing caesarean delivery compared to epidural analgesia.

METHODS

Participants were divided into parallel groups: an experimental group receiving TAP block (n=25) and a control group receiving epidural analgesia (n=24). All patients received a 10 mg dose of hyoscine at the end of the surgery. Experimental Group received a total of 20 mL of 0.2% ropivacaine. In Epidural group received 0.2% ropivacaine at 4 mL/h for 24 hours. All participants were administered combined with neuroaxial block anesthesia. The patients selected for epidural analgesia received the mentioned dose, while the other group block had the epidural catheter removed after the cesarean section. The primary outcome was post-caesarean pain, evaluated using the Visual Analog Scale (VAS) at four intervals (0, 6, 12, and 24 hours). Also, surgical bleeding and residual motor were evaluated. VAS pain scores between the groups were compared using the Friedman test and Generalized Linear Model (GLM) for non-normally distributed data. The effect size was estimated with Eta Square ([Formula: see text]), considering values ≥0.38 as indicative of large effects. A two-tailed p-value < 0.05 was deemed statistically significant.

RESULTS

Statistically significant differences in pain scores were noted at 0 and 6 hours post-surgery (p<0.01). The TAP block group reported lower pain scores at 0 hours (mean=0.04) and 6 hours (mean=1.16) compared to the epidural group, reflecting a substantial effect size.

CONCLUSION

The TAP block proves advantageous in mitigating postoperative pain for women post-caesarean delivery, particularly in the initial 6 postpartum hours. This relief promotes early mother-infant bonding and facilitates breastfeeding.

摘要

背景

有效的术后镇痛对剖宫产术后患者的恢复和预后有深远影响。腹横肌平面(TAP)阻滞是一种潜在的替代方法,可能比硬膜外镇痛更有效,且不良反应更少。

目的

评估与硬膜外镇痛相比,腹横肌阻滞在剖宫产患者中是否能提供更好的术后疼痛缓解。

方法

将参与者分为平行组:实验组接受TAP阻滞(n = 25),对照组接受硬膜外镇痛(n = 24)。所有患者在手术结束时接受10mg剂量的东莨菪碱。实验组共接受20mL 0.2%的罗哌卡因。硬膜外组以4mL/h的速度接受0.2%的罗哌卡因,持续24小时。所有参与者均接受联合腰麻-硬膜外麻醉。选择硬膜外镇痛的患者接受上述剂量,而另一组在剖宫产术后拔除硬膜外导管。主要结局是剖宫产术后疼痛,在四个时间点(0、6、12和24小时)使用视觉模拟量表(VAS)进行评估。此外,还评估了手术出血量和残余运动功能。使用Friedman检验和广义线性模型(GLM)对非正态分布数据比较两组之间的VAS疼痛评分。使用Eta平方([公式:见正文])估计效应大小,将≥0.38的值视为大效应的指标。双侧p值<0.05被认为具有统计学意义。

结果

术后0小时和6小时疼痛评分存在统计学显著差异(p<0.01)。与硬膜外组相比,TAP阻滞组在0小时(平均=0.04)和6小时(平均=1.16)报告的疼痛评分更低,反映出较大的效应大小。

结论

TAP阻滞被证明在减轻剖宫产术后女性的术后疼痛方面具有优势,尤其是在产后最初6小时。这种疼痛缓解促进了母婴早期亲密接触并便于母乳喂养。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/53cc/11033210/d73050febbcd/LRA-17-39-g0001.jpg

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