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[传染病中的紧急情况]

[Emergencies in infectious diseases].

作者信息

Brehm Thomas Theo, Matthews Hanna, Hennigs Annette

机构信息

I. Medizinische Klinik und Poliklinik, Sektion Infektiologie, Universitätsklinikum Hamburg-Eppendorf, Martinistr. 42, 20246, Hamburg, Deutschland.

Ambulanzzentrum für Infektiologie, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Deutschland.

出版信息

Med Klin Intensivmed Notfmed. 2024 Jun;119(5):408-418. doi: 10.1007/s00063-024-01147-7. Epub 2024 Apr 23.

DOI:10.1007/s00063-024-01147-7
PMID:38652143
Abstract

This article aims to provide an overview of common and high-impact medical emergencies that require prompt and effective infectious diseases management. In the described clinical scenarios of malaria, sepsis, necrotizing fasciitis, and meningitis the authors have emphasized the crucial importance of rapid and accurate diagnosis, as well as appropriate treatment from the perspective of infectious diseases. All of these emergencies demand a high degree of clinical suspicion for accurate diagnosis. Some of them also necessitate the involvement of other medical disciplines, such as neurology in the case of meningitis or surgery for necrotizing fasciitis. Additionally, implementing the right empiric antibiotic regimen or, in the case of malaria, antiparasitic treatment is crucial for improving patient outcomes. As patients with these diagnoses may present at any outpatient department, and efficient and quick management is essential, a deep understanding of diagnostic algorithms and potential pitfalls is of the utmost importance.

摘要

本文旨在概述需要及时、有效进行传染病管理的常见且影响重大的医疗紧急情况。在所描述的疟疾、败血症、坏死性筋膜炎和脑膜炎的临床案例中,作者强调了从传染病角度进行快速准确诊断以及适当治疗的至关重要性。所有这些紧急情况都需要高度的临床怀疑以进行准确诊断。其中一些情况还需要其他医学学科的参与,例如脑膜炎需要神经内科参与,坏死性筋膜炎需要外科参与。此外,实施正确的经验性抗生素治疗方案,或者在疟疾情况下进行抗寄生虫治疗,对于改善患者预后至关重要。由于患有这些疾病的患者可能出现在任何门诊科室,高效快速的管理至关重要,因此深入理解诊断算法和潜在陷阱极为重要。

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1
[Emergencies in infectious diseases].[传染病中的紧急情况]
Med Klin Intensivmed Notfmed. 2024 Jun;119(5):408-418. doi: 10.1007/s00063-024-01147-7. Epub 2024 Apr 23.
2
[Emergencies in infectious diseases].[传染病中的紧急情况]
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Necrotizing fasciitis and meningitis due to Streptococcus pneumoniae serotype 9 N: a case report.由 9 型肺炎链球菌引起的坏死性筋膜炎和脑膜炎:一例报告。
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Necrotizing fasciitis.坏死性筋膜炎
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本文引用的文献

1
Post-treatment haemolysis is common following oral artemisinin combination therapy of uncomplicated malaria in travellers.旅行者在接受口服青蒿素类复方药物治疗无并发症疟疾后常会出现治疗后溶血。
J Travel Med. 2023 May 18;30(3). doi: 10.1093/jtm/taad001.
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Biofire FilmArray Meningitis/Encephalitis panel for the aetiological diagnosis of central nervous system infections: A systematic review and diagnostic test accuracy meta-analysis.用于中枢神经系统感染病因诊断的Biofire FilmArray脑膜炎/脑炎检测板:系统评价与诊断试验准确性的Meta分析
EClinicalMedicine. 2022 Feb 14;44:101275. doi: 10.1016/j.eclinm.2022.101275. eCollection 2022 Feb.
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Surviving sepsis campaign: international guidelines for management of sepsis and septic shock 2021.
拯救脓毒症运动:2021年脓毒症和脓毒性休克国际管理指南
Intensive Care Med. 2021 Nov;47(11):1181-1247. doi: 10.1007/s00134-021-06506-y. Epub 2021 Oct 2.
4
[Non-cholera Vibrio species - currently still rare but growing danger of infection in the North Sea and the Baltic Sea].[非霍乱弧菌属——目前仍然罕见,但在北海和波罗的海的感染风险正在增加]
Internist (Berl). 2021 Aug;62(8):876-886. doi: 10.1007/s00108-021-01086-x. Epub 2021 Jul 16.
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Pneumococcal Meningitis in Adults: A Prospective Nationwide Cohort Study Over a 20-year Period.成人肺炎球菌性脑膜炎:20 年期间一项前瞻性全国队列研究。
Clin Infect Dis. 2022 Mar 1;74(4):657-667. doi: 10.1093/cid/ciab477.
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[Sepsis incidence in Germany and worldwide : Current knowledge and limitations of research using health claims data].[德国及全球的脓毒症发病率:利用健康声明数据进行研究的现状与局限]
Med Klin Intensivmed Notfmed. 2022 May;117(4):264-268. doi: 10.1007/s00063-021-00777-5. Epub 2021 Jan 28.
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Risk Factors and Predictors of Mortality in Streptococcal Necrotizing Soft-tissue Infections: A Multicenter Prospective Study.链球菌坏死性软组织感染的死亡风险因素和预测因素:一项多中心前瞻性研究。
Clin Infect Dis. 2021 Jan 27;72(2):293-300. doi: 10.1093/cid/ciaa027.
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Time to Treatment and Mortality during Mandated Emergency Care for Sepsis.脓毒症强制紧急治疗的治疗时间与死亡率
N Engl J Med. 2017 Jun 8;376(23):2235-2244. doi: 10.1056/NEJMoa1703058. Epub 2017 May 21.
9
Immunoglobulin G for patients with necrotising soft tissue infection (INSTINCT): a randomised, blinded, placebo-controlled trial.免疫球蛋白 G 治疗坏死性软组织感染的疗效(INSTINCT):一项随机、双盲、安慰剂对照试验。
Intensive Care Med. 2017 Nov;43(11):1585-1593. doi: 10.1007/s00134-017-4786-0. Epub 2017 Apr 18.
10
The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3).《脓毒症及脓毒性休克第三次国际共识定义(脓毒症-3)》
JAMA. 2016 Feb 23;315(8):801-10. doi: 10.1001/jama.2016.0287.