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肥胖与非肥胖腰椎间盘突出症患者接受全内镜下经椎间孔椎间盘切除术的比较结果:一项系统评价和荟萃分析

Comparative outcomes of obese and non-obese patients with lumbar disc herniation receiving full endoscopic transforaminal discectomy: a systematic review and meta-analysis.

作者信息

Feng An-Ping, Yu Shang-Feng, Chen Chien-Min, He Li-Ru, Jhang Shang-Wun, Lin Guang-Xun

机构信息

Department of Orthopedics and Traumatology of Traditional Chinese Medicine, The Third Hospital of Xiamen, Xiamen, China.

Department of clinical laboratory, The Third Hospital of Xiamen, Xiamen, China.

出版信息

BMC Musculoskelet Disord. 2024 Apr 23;25(1):322. doi: 10.1186/s12891-024-07455-5.

Abstract

OBJECTIVE

This study aimed to assess the impact of full endoscopic transforaminal discectomy (FETD) on clinical outcomes and complications in both obese and non-obese patients presenting with lumbar disc herniation (LDH).

METHODS

A systematic search of relevant literature was conducted across various primary databases until November 18, 2023. Operative time and hospitalization were evaluated. Clinical outcomes included preoperative and postoperative assessments of the Oswestry Disability Index (ODI) and visual analogue scale (VAS) scores, conducted to delineate improvements at 3 months postoperatively and during the final follow-up, respectively. Complications were also documented.

RESULTS

Four retrospective studies meeting inclusion criteria provided a collective cohort of 258 patients. Obese patients undergoing FETD experienced significantly longer operative times compared to non-obese counterparts (P = 0.0003). Conversely, no statistically significant differences (P > 0.05) were observed in hospitalization duration, improvement of VAS for back and leg pain scores at 3 months postoperatively and final follow-up, improvement of ODI at 3 months postoperatively and final follow-up. Furthermore, the overall rate of postoperative complications was higher in the obese group (P = 0.02). The obese group demonstrated a total incidence of complications of 17.17%, notably higher than the lower rate of 9.43% observed in the non-obese group.

CONCLUSION

The utilization of FETD for managing LDH in individuals with obesity is associated with prolonged operative times and a higher total complication rate compared to their non-obese counterparts. Nevertheless, it remains a safe and effective surgical intervention for treating herniated lumbar discs in the context of obesity.

摘要

目的

本研究旨在评估全内镜经椎间孔椎间盘切除术(FETD)对肥胖和非肥胖腰椎间盘突出症(LDH)患者临床结局及并发症的影响。

方法

截至2023年11月18日,在多个主要数据库中对相关文献进行系统检索。评估手术时间和住院时间。临床结局包括术前和术后对Oswestry功能障碍指数(ODI)和视觉模拟量表(VAS)评分的评估,分别用于描述术后3个月和末次随访时的改善情况。并发症也进行了记录。

结果

四项符合纳入标准的回顾性研究共纳入258例患者。与非肥胖患者相比,接受FETD的肥胖患者手术时间明显更长(P = 0.0003)。相反,在住院时间、术后3个月和末次随访时腰腿痛VAS评分的改善、术后3个月和末次随访时ODI的改善方面,未观察到统计学显著差异(P > 0.05)。此外,肥胖组术后并发症的总体发生率更高(P = 0.02)。肥胖组并发症的总发生率为17.17%,明显高于非肥胖组观察到的9.43%的较低发生率。

结论

与非肥胖患者相比,采用FETD治疗肥胖个体的LDH手术时间延长,总并发症发生率更高。然而,在肥胖情况下,它仍然是治疗腰椎间盘突出症的一种安全有效的手术干预方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3b9c/11040856/52db2bb3b353/12891_2024_7455_Fig1_HTML.jpg

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