Stoddart Michael T, Panagopoulos Georgios N, Craig Richard S, Falworth Mark, Butt David, Rudge Will, Higgs Deborah, Majed Addie
Shoulder & Elbow Service, Royal National Orthopaedic Hospital, Stanmore, UK.
Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences (NDORMS), Botnar Research Centre, University of Oxford, Oxford, UK.
Shoulder Elbow. 2024 Apr;16(2):175-185. doi: 10.1177/17585732221099845. Epub 2022 May 9.
Fractures of the distal humerus are a common fragility fracture in older adults. The purpose of this study was to systematically review the literature to produce pooled estimates of the outcomes of treatment using total elbow arthroplasty (TEA), open reduction and locking plate fixation (ORIF), hemiarthroplasty or with conservative management.
A systematic review of PUBMED and EMBASE databases was conducted for studies reporting outcomes of intra-articular fractures in older adults. Data extracted included patient-reported outcome measures as well as clinical outcomes including ROM, adverse events and all-cause reoperation rates.
Forty-eight studies met the inclusion criteria and included 1838 acute, intra-articular distal humeral fractures. There was no clinically important difference in patient-reported pain and function measured on the Mayo Elbow Performance Score (TEA = 89.3 (SD 20.0), Hemi = 88.4 (SD 10.6), internal fixation = 85.0 (SD 14.7), non-operative = 85.1 (SD 11.0)).
Each of the treatment modalities studies resulted in a reasonable level of elbow function. The included studies were largely non-comparative and at considerable risk of bias. As elbow replacement surgery becomes centralised in the UK, there is a real need for high-quality comparative research studies to inform practice.
肱骨远端骨折是老年人常见的脆性骨折。本研究的目的是系统回顾文献,以汇总估计全肘关节置换术(TEA)、切开复位锁定钢板固定术(ORIF)、半关节置换术或保守治疗的疗效。
对PUBMED和EMBASE数据库进行系统回顾,以查找报告老年人关节内骨折治疗结果的研究。提取的数据包括患者报告的结局指标以及临床结局,如关节活动度、不良事件和全因再手术率。
48项研究符合纳入标准,共纳入1838例急性关节内肱骨远端骨折。根据梅奥肘关节功能评分,患者报告的疼痛和功能在各治疗组间无临床显著差异(TEA组=89.3(标准差20.0),半关节置换术组=88.4(标准差10.6),内固定组=85.0(标准差14.7),非手术组=85.1(标准差11.0))。
所研究的每种治疗方式均能带来合理的肘关节功能水平。纳入的研究大多为非对比性研究,存在相当大的偏倚风险。随着肘关节置换手术在英国逐渐集中化,亟需高质量的对比研究为临床实践提供参考。