Gao Yuan, Li Ming, Jiang Miaowen, Zhang Yang, Ji Xunming
School of Instrumentation and Optoelectronic Engineering, Beihang University, Beijing, China.
Research Institute for Frontier Science, Beihang University, Beijing, China.
Brain Circ. 2024 Mar 21;10(1):11-20. doi: 10.4103/bc.bc_32_23. eCollection 2024 Jan-Mar.
Therapeutic hypothermia (TH) has been regarded as a promising neuroprotective method for acute ischemic stroke (AIS) for decades. During the development of TH, most researchers focused on improving hypothermic benefits by optimizing treatment processes and conditions. Intravenous thrombolysis and endovascular thrombectomy, for instance, have been introduced into AIS treatment. However, the lack of specialized intervention consumables, especially intervention catheter, led to inaccurate and uncontrolled hypothermic temperature, limited the efficacy of TH. In this review, intervention catheters as well as accessory equipment utilized in TH treatment has been summarized. Hopefully, this review may inspire the future development of TH specialized intervention catheter, enhance the outcome of TH, and neuroprotective efficacy in AIS.
几十年来，治疗性低温（TH）一直被视为急性缺血性卒中（AIS）一种很有前景的神经保护方法。在TH的发展过程中，大多数研究人员专注于通过优化治疗过程和条件来提高低温治疗的益处。例如，静脉溶栓和血管内血栓切除术已被引入AIS治疗。然而，缺乏专门的介入耗材，尤其是介入导管，导致低温温度不准确且无法控制，限制了TH的疗效。在这篇综述中，总结了TH治疗中使用的介入导管以及辅助设备。希望这篇综述能够启发TH专用介入导管的未来发展，提高TH的治疗效果以及在AIS中的神经保护疗效。
