Suppr超能文献

对比 2022 年 5 月 9 日全球造影剂短缺前后钝器伤创伤患者行胸腹部骨盆 CT 检查时静脉碘对比剂的应用和效用:一家二级创伤中心的经验

Comparison and Utility of Intravenous Iodinated Contrast in Chest, Abdomen, Pelvis Computerized Tomography for Trauma Patients With Blunt Mechanism of Injury Before and After the May 9, 2022 Global Contrast Shortage at a Level II Trauma Center.

机构信息

Department of Surgery, Huntington Health, Pasadena, CA, USA.

出版信息

Am Surg. 2024 Oct;90(10):2494-2500. doi: 10.1177/00031348241248806. Epub 2024 Apr 24.

Abstract

Intravenous (IV) contrast improves the sensitivity and specificity of injury detection in computerized tomography (CT). Its use is recommended in the workup of trauma patients by the American College of Surgeons and American College of Radiology. On May 9, 2022, the Food and Drug Administration declared a shortage of iodinated contrast due to the COVID-19 pandemic. Although the shortage has ended, the temporary lack of IV contrast forced physicians to be prudent in ordering CT scans with IV contrast. We sought to determine if there was a change in the percentage of CT contrast studies performed during the contrast shortage and if this change affected patient outcomes. Retrospective chart review was performed on all adult tier 2 trauma patients at a 619-bed community-based level II trauma center who received CT chest, abdomen, and pelvis imaging as initial workup for blunt trauma from 5/9/2021-6/30/2021 (pre-shortage) and 5/9/2022-6/30/2022 (during shortage). Patients were predominantly male with median age of 31-52 and of White or Hispanic ethnicity. Before the contrast shortage, all 110 trauma patients were scanned with contrast. During the shortage, 29 of 114 patients were scanned with contrast ( < 0.001). Injuries were identified in 59% of patients scanned with contrast ( < 0.001). There were no significant differences in blood transfusion needs, repeat CT, disposition, or mortality when comparing pre-shortage to during shortage or when comparing between non-contrast and contrast studies during the shortage. There was a decrease in the percentage of CT contrast studies performed during the shortage. A higher percentage of injuries were identified in the patients scanned with contrast. However, there were no significant differences in patient outcomes. Certain trauma patients may be safely scanned without contrast.

摘要

静脉(IV)造影剂可提高计算机断层扫描(CT)中损伤检测的敏感性和特异性。美国外科医师学院和美国放射学院建议在创伤患者的检查中使用造影剂。2022 年 5 月 9 日,由于 COVID-19 大流行,食品和药物管理局宣布碘造影剂短缺。尽管短缺已经结束,但暂时缺乏 IV 造影剂迫使医生在开具 IV 造影 CT 扫描时谨慎行事。我们试图确定在造影剂短缺期间进行 CT 造影研究的百分比是否发生了变化,以及这种变化是否影响了患者的结局。对一家拥有 619 张床位的社区二级创伤中心的所有成年二级创伤患者进行了回顾性图表审查,这些患者在 2021 年 5 月 9 日至 2021 年 6 月 30 日(短缺前)和 2022 年 5 月 9 日至 2022 年 6 月 30 日(期间)期间,因钝器伤接受了胸部、腹部和骨盆 CT 成像作为初始检查。患者主要为男性,中位年龄为 31-52 岁,为白种人或西班牙裔。在造影剂短缺之前,所有 110 名创伤患者均进行了造影扫描。在短缺期间,114 名患者中有 29 名(<0.001)进行了造影扫描。在接受造影扫描的患者中,59%(<0.001)发现了损伤。在比较短缺前和短缺期间,或在比较短缺期间的非造影和造影研究时,比较输血需求、重复 CT、处置或死亡率,没有显著差异。在短缺期间,进行 CT 造影研究的百分比有所下降。在接受造影扫描的患者中,发现损伤的比例更高。然而,患者的结局没有显著差异。某些创伤患者可以安全地不进行造影扫描。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验