Turan Şenol, Özulucan Mahmut Taha, Karataş Uğur, Kavla Yasin, Koyuncu Oğuzhan, Durcan Emre, Durcan Gizem, Bağhaki Semih
Department of Psychiatry, Cerrahpasa Medical Faculty, Istanbul University-Cerrahpasa, Istanbul, Türkiye.
Graduate School of Health Science, Neuroscience PhD Program, Koç University, Istanbul, Türkiye.
Qual Life Res. 2024 Jul;33(7):1937-1947. doi: 10.1007/s11136-024-03664-6. Epub 2024 Apr 24.
Individuals with gender dysphoria (GD) may request hormone therapy and various surgical operations to change their physical characteristics. The present study aimed to investigate the effects of two treatments, mastectomy and gender-affirming hormone therapy (GAHT), on adults with GD who were assigned female at birth (GD AFAB).
In this cross-sectional study, we gathered data from a total of 269 individuals in three groups: (a) untreated group (n = 121), (b) GAHT group (n = 84) who had been receiving treatment for at least 6 months, and (c) GAHT-MAST group (n = 64) who had been using GAHT for at least 6 months and had undergone mastectomy at least 3 months prior. All participants were asked to complete the Symptom Checklist-90-Revised (SCL-90-R), the Body Uneasiness Test (BUT), and the World Health Organization's Quality of Life Questionnaire- Brief Form, Turkish Version (WHOQOL-BREF-Tr).
We found that individuals in the untreated group had higher psychopathological symptoms and body uneasiness scores, and lower quality of life scores compared to both GAHT and GAHT-MAST groups. There was no difference in psychopathology between the GAHT-MAST group and the GAHT group, but body uneasiness scores were lower, and quality of life scores were higher in the GAHT-MAST group.
Our study suggests that individuals receiving GAHT improved mental health, body satisfaction, and overall quality of life. Combining mastectomy with GAHT may further enhance these benefits.
患有性别焦虑症（GD）的个体可能会要求进行激素治疗和各种外科手术来改变他们的身体特征。本研究旨在调查两种治疗方法，即乳房切除术和性别确认激素疗法（GAHT），对出生时被指定为女性的成年GD患者（GD AFAB）的影响。
在这项横断面研究中，我们收集了三组共269名个体的数据：（a）未治疗组（n = 121），（b）接受治疗至少6个月的GAHT组（n = 84），以及（c）使用GAHT至少6个月且至少在3个月前接受过乳房切除术的GAHT - MAST组（n = 64）。所有参与者都被要求完成症状自评量表-修订版（SCL - 90 - R）、身体不适感测试（BUT）以及世界卫生组织生活质量问卷简表土耳其语版（WHOQOL - BREF - Tr）。
我们发现，与GAHT组和GAHT - MAST组相比，未治疗组个体的心理病理症状和身体不适感得分更高，生活质量得分更低。GAHT - MAST组和GAHT组在心理病理学方面没有差异，但GAHT - MAST组的身体不适感得分更低，生活质量得分更高。
我们的研究表明，接受GAHT的个体心理健康、身体满意度和总体生活质量得到改善。将乳房切除术与GAHT相结合可能会进一步增强这些益处。
