Zhang Shaofei, Ouyang Xu, Yang Kefei, Shen Yunyun, Zheng Siyuan, Wang Ruoqi, Sheng Xuanlian, Ge Menglin, Yang Meng, Zhou Xiaoqin
School of Mental Health and Psychological Sciences, Anhui Medical University, Hefei City, People's Republic of China.
Second Affiliated Hospital of Anhui Medical University, Hefei City, People's Republic of China.
Psychol Res Behav Manag. 2024 Apr 20;17:1717-1726. doi: 10.2147/PRBM.S453891. eCollection 2024.
In schizophrenia, aggressive conduct is frequent. And depressed mood can also contribute to the occurrence of aggressive behaviors. The aim of this study was to investigate the risk factors for the occurrence of aggression in stable schizophrenia patients in rural China, mainly to investigate the role of depressed mood in the occurrence of aggression in schizophrenia patients.
This is a cross-sectional study conducted in the townships surrounding Chaohu City, Anhui Province, China. Patients' depressive mood was evaluated using the PHQ-9 (The 9-item Patient Health Questionnaire). Patients' aggressiveness was evaluated using the Modified Overt Aggression Scale (MOAS). A score of ≥4 was used as a threshold and divided into aggressive and non-aggressive groups.
This study comprised a total of 821 schizophrenia patients. Among them, the prevalence of having aggressive behavior was 18.8%. After correcting for confounders, logistic regression analysis showed that low education level (OR=0.470, 95% CI 0.254-0.870; p=0.016), living with family (OR=0.383, 95% CI 0.174-0.845; p=0.017) depressed mood (OR=1.147, 95% CI 1.112-1.184; p<0.001) was significantly associated with the risk of aggressive behavior in patients with schizophrenia. Multivariate linear regression indicated that higher levels of aggression were linked with lower levels of education and higher depressive mood.
This study suggests that aggression is more common in patients with stable schizophrenia, and lower levels of education and higher levels of depression are associated risk factors for its occurrence. Living alone may be helpful in reducing the likelihood of aggression.
在精神分裂症中，攻击行为很常见。而且抑郁情绪也可能导致攻击行为的发生。本研究的目的是调查中国农村稳定期精神分裂症患者攻击行为发生的危险因素，主要是调查抑郁情绪在精神分裂症患者攻击行为发生中的作用。
这是一项在中国安徽省巢湖市周边乡镇进行的横断面研究。使用PHQ-9（9项患者健康问卷）评估患者的抑郁情绪。使用改良的公开攻击量表（MOAS）评估患者的攻击性。以≥4分为阈值，分为攻击组和非攻击组。
本研究共纳入821例精神分裂症患者。其中，有攻击行为的患病率为18.8%。校正混杂因素后，逻辑回归分析显示，低教育水平（OR=0.470，95%CI 0.254-0.870；p=0.016）、与家人同住（OR=0.383，95%CI 0.174-0.845；p=0.017）、抑郁情绪（OR=1.147，95%CI 1.112-1.184；p<0.001）与精神分裂症患者攻击行为的风险显著相关。多元线性回归表明，较高水平的攻击行为与较低的教育水平和较高的抑郁情绪有关。
本研究表明，攻击行为在稳定期精神分裂症患者中更为常见，较低的教育水平和较高的抑郁水平是其发生的相关危险因素。独居可能有助于降低攻击行为的可能性。
