Kobashi H, Nishioka A, Miyamoto N, Ohara K, Okamoto T
Jpn J Antibiot. 1985 Oct;38(10):2932-42.
Ceftizoxime suppositories (CZX-S), containing 250 mg or 125 mg of CZX, were given to 6 children, 4 with acute bronchopneumonia and 2 with acute pharyngobronchitis, who were not suited to treatment with injectable or oral form of the drug. The clinical response was "good" in all the children and the causative organisms were eradicated in 2 children (H. influenzae or S. aureus). Adverse reactions consisted of 1 case each of diarrhea and transiently increased GPT. In conclusion, CZX-S proved to be highly effective in the treatment of bacterial infections in children.
头孢唑肟栓剂（CZX-S），含250毫克或125毫克头孢唑肟，给予6名儿童，其中4名患有急性支气管肺炎，2名患有急性咽支气管炎，这些儿童不适合使用该药物的注射剂或口服剂型。所有儿童的临床反应均为“良好”，2名儿童（流感嗜血杆菌或金黄色葡萄球菌）的致病微生物被根除。不良反应包括腹泻和谷丙转氨酶短暂升高各1例。总之，头孢唑肟栓剂被证明在治疗儿童细菌感染方面非常有效。
