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Intrahepatic Cholangiocarcinoma With Extrahepatic Metastasis and High Tumor Mutation Burden: Case of Complete Pathological Response to Cisplatin/Gemcitabine/Pembrolizumab.

作者信息

Robinson Matthew D, Wheatley Roseanna, Foster Lucy, Jamdar Saurabh, Siriwardena Ajith K, Lamarca Angela, Hubner Richard, Valle Juan W, McNamara Mairéad G

机构信息

Division of Cancer Sciences, School of Medical Sciences, Faculty of Biology Medicine and Health, The University of Manchester, Manchester, United Kingdom.

Department of Medical Oncology, The Christie NHS Foundation Trust, Wilmslow Road, Manchester, United Kingdom.

出版信息

JCO Precis Oncol. 2024 Apr;8:e2300572. doi: 10.1200/PO.23.00572.

DOI:10.1200/PO.23.00572
PMID:38662981
Abstract
摘要

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引用本文的文献

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Surg Case Rep. 2025;11(1). doi: 10.70352/scrj.cr.25-0025. Epub 2025 Apr 25.
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Pathological complete response following addition of durvalumab to gemcitabine and cisplatin therapy for intrahepatic cholangiocarcinoma with Lynch syndrome-associated mismatch repair deficiency.在吉西他滨和顺铂治疗基础上加用度伐利尤单抗治疗林奇综合征相关错配修复缺陷的肝内胆管癌后的病理完全缓解。
Clin J Gastroenterol. 2025 Jun;18(3):520-526. doi: 10.1007/s12328-025-02122-1. Epub 2025 Apr 10.