Ghanooni Amir Hossein, KazemiJahromi Mitra, Hosseinpanah Farhad
Department of Endocrinology, School of Medicine, Iran University of Medical Sciences, Tehran, Iran.
Endocrinology and Metabolism Research Center, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Int J Endocrinol Metab. 2023 Dec 13;22(1):e138703. doi: 10.5812/ijem-138703. eCollection 2024 Jan.
Primary aldosteronism (PA) is a clinical syndrome characterized by hypertension, suppressed plasma renin activity (PRA), elevated plasma aldosterone concentration (PAC), and spontaneous hypokalemia.
We present a 37-year-old normotensive female with hypokalemia, high plasma aldosterone level, and suppressed renin. The patient was treated with eplerenone and potassium chloride supplement. Further investigation with a computed tomography (CT) scan revealed a mass in the left adrenal. Laparoscopic adrenalectomy led to the diagnosis of adrenal adenoma.
Primary aldosteronism should be among the differential diagnoses in normotensive patients presenting with severe hypokalemia.
原发性醛固酮增多症(PA)是一种临床综合征,其特征为高血压、血浆肾素活性(PRA)受抑制、血浆醛固酮浓度(PAC)升高以及自发性低钾血症。
我们报告一名37岁血压正常的女性,伴有低钾血症、血浆醛固酮水平升高和肾素受抑制。该患者接受依普利酮和补充氯化钾治疗。进一步的计算机断层扫描(CT)检查发现左肾上腺有一个肿块。腹腔镜肾上腺切除术确诊为肾上腺腺瘤。
对于出现严重低钾血症的血压正常患者,原发性醛固酮增多症应列入鉴别诊断范围。