Chao An-Shine, Jhang Lan-Sin, Hsieh Peter Ching-Chang
Department of Obstetrics and Gynecology, New Taipei Municipal Tucheng Hospital, New Taipei, Taiwan.
Department of Obstetrics and Gynecology, Chang Gung Memorial Hospital and University, Taoyuan, Taiwan.
J Med Ultrasound. 2024 Jan 10;32(1):21-24. doi: 10.4103/jmu.jmu_51_23. eCollection 2024 Jan-Mar.
Prenatal diagnosis of myelomeningocele remains challenging for obstetricians, ultrasonographers, and radiologists, although the increased maternal serum alpha-fetoprotein level aids in the confirmative diagnosis. Fetal cervical myelomeningocele and meningocele are very rare and unique types of myelomeningocele. Prenatal diagnosis of cervical myelomeningocele and meningocele should include the differential diagnosis and association of many intracranial and spino-skeletal pathogenetic variants and genetic diseases, including subependymal nodular heterotopia and Klippel-Feil syndrome. In this report, a comprehensive review of fetal cervical myelomeningocele with its prenatal diagnosis and long-term outcomes is presented.
尽管孕妇血清甲胎蛋白水平升高有助于确诊，但脊髓脊膜膨出的产前诊断对产科医生、超声检查医师和放射科医生来说仍然具有挑战性。胎儿颈部脊髓脊膜膨出和脊膜膨出是非常罕见且独特的脊髓脊膜膨出类型。颈部脊髓脊膜膨出和脊膜膨出的产前诊断应包括许多颅内和脊柱骨骼致病变异及遗传疾病的鉴别诊断和关联，包括室管膜下结节性异位和克利佩尔-费尔综合征。在本报告中，对胎儿颈部脊髓脊膜膨出及其产前诊断和长期预后进行了全面综述。
