Department of Cardiology, University of Michigan, 1500 East Medical Center Drive, Ann Arbor, 48109 MI, USA.
Department of Cardiology, University Heart Center Zurich, Raemistrasse 100, Zurich 8091, Switzerland.
Europace. 2024 May 2;26(5). doi: 10.1093/europace/euae110.
Stereotactic arrhythmia radioablation (STAR) is a treatment option for recurrent ventricular tachycardia/fibrillation (VT/VF) in patients with structural heart disease (SHD). The current and future role of STAR as viewed by cardiologists is unknown. The study aimed to assess the current role, barriers to application, and expected future role of STAR. An online survey consisting of 20 questions on baseline demographics, awareness/access, current use, and the future role of STAR was conducted. A total of 129 international participants completed the survey [mean age 43 ± 11 years, 25 (16.4%) female]. Ninety-one (59.9%) participants were electrophysiologists. Nine participants (7%) were unaware of STAR as a therapeutic option. Sixty-four (49.6%) had access to STAR, while 62 (48.1%) had treated/referred a patient for treatment. Common primary indications for STAR were recurrent VT/VF in SHD (45%), recurrent VT/VF without SHD (7.8%), or premature ventricular contraction (3.9%). Reported main advantages of STAR were efficacy in the treatment of arrhythmias not amenable to conventional treatment (49%) and non-invasive treatment approach with overall low expected acute and short-term procedural risk (23%). Most respondents have foreseen a future clinical role of STAR in the treatment of VT/VF with or without underlying SHD (72% and 75%, respectively), although only a minority expected a first-line indication for it (7% and 5%, respectively). Stereotactic arrhythmia radioablation as a novel treatment option of recurrent VT appears to gain acceptance within the cardiology community. Further trials are critical to further define efficacy, patient populations, as well as the appropriate clinical use for the treatment of VT.
立体定向心律失常消融术(STAR)是结构性心脏病(SHD)患者复发性室性心动过速/颤动(VT/VF)的一种治疗选择。目前,心脏病专家对 STAR 的作用存在争议,未来的作用也不明确。本研究旨在评估 STAR 的当前作用、应用障碍以及未来的预期作用。我们进行了一项在线调查,共包含 20 个问题,涉及基本人口统计学、意识/获取途径、当前使用情况以及 STAR 的未来作用。共有 129 名国际参与者完成了这项调查(平均年龄为 43 ± 11 岁,25 名女性[16.4%])。91 名参与者(59.9%)为电生理学家。有 9 名参与者(7%)不了解 STAR 作为一种治疗选择。64 名参与者(49.6%)有 STAR 的使用途径,62 名参与者(48.1%)曾为患者进行过治疗或推荐过 STAR 治疗。STAR 的常见主要适应证为 SHD 患者的复发性 VT/VF(45%)、非 SHD 患者的复发性 VT/VF(7.8%)或室性期前收缩(3.9%)。报告的 STAR 的主要优势为在治疗常规治疗无效的心律失常方面具有疗效(49%),且治疗方法为非侵入性,预计急性和短期手术风险总体较低(23%)。大多数受访者认为 STAR 在治疗伴有或不伴有潜在 SHD 的 VT/VF 方面具有未来的临床作用(分别为 72%和 75%),尽管只有少数人预计它将成为一线治疗方法(分别为 7%和 5%)。立体定向心律失常消融术作为复发性 VT 的一种新的治疗选择,在心脏病学界得到了认可。进一步的临床试验对于进一步明确其疗效、患者人群以及治疗 VT 的适当临床应用至关重要。