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立体定向心律失常射频消融术(STAR)综合综述:开创心律失常管理新时代

A Comprehensive Review on Stereotactic Arrhythmia Radioablation (STAR): Pioneering a New Era in Arrhythmia Management.

作者信息

Thawkar Varun N, Taksande Karuna

机构信息

Anaesthesiology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education & Research, Wardha, IND.

出版信息

Cureus. 2024 Oct 1;16(10):e70601. doi: 10.7759/cureus.70601. eCollection 2024 Oct.

Abstract

Stereotactic arrhythmia radioablation (STAR) is an innovative treatment modality that leverages advanced imaging techniques and focused radiation to target arrhythmogenic foci within the heart, offering a non-invasive alternative to traditional catheter ablation methods. Arrhythmias, characterized by irregular heartbeats, pose significant health risks, including heart failure and stroke, particularly among older adults. Traditional management approaches, such as pharmacological therapies and catheter ablation, often face efficacy, safety, and recurrence limitations. STAR addresses these challenges by utilizing high-precision stereotactic technology to deliver targeted radiation, minimizing damage to surrounding tissues while maximizing therapeutic effects. This review explores the mechanisms, clinical indications, procedural techniques, and outcomes associated with STAR. Recent clinical studies demonstrate that STAR provides comparable efficacy to catheter ablation, with a favorable safety profile, making it a promising option for patients who have not responded to conventional treatments. Integrating STAR into arrhythmia management protocols may enhance patient outcomes and reduce the burden of recurrent arrhythmias. As research in this field advances, STAR holds the potential to reshape the landscape of arrhythmia treatment, providing new hope for patients suffering from these complex conditions. This review aims to elucidate the significance of STAR in modern arrhythmia management and to encourage further exploration and clinical application of this pioneering technique.

摘要

立体定向心律失常放射消融术(STAR)是一种创新的治疗方式,它利用先进的成像技术和聚焦辐射来靶向心脏内的致心律失常病灶,为传统导管消融方法提供了一种非侵入性替代方案。心律失常以心跳不规则为特征,会带来重大健康风险,包括心力衰竭和中风,在老年人中尤为常见。传统的治疗方法,如药物治疗和导管消融,常常面临疗效、安全性和复发率方面的限制。STAR通过利用高精度立体定向技术来提供靶向辐射,在最大限度减少对周围组织损伤的同时最大化治疗效果,从而应对这些挑战。本综述探讨了与STAR相关的机制、临床适应症、操作技术和治疗结果。近期临床研究表明,STAR与导管消融具有相当的疗效,且安全性良好,对于那些对传统治疗无反应的患者来说是一个有前景的选择。将STAR纳入心律失常管理方案可能会改善患者预后并减轻复发性心律失常的负担。随着该领域研究的进展,STAR有望重塑心律失常治疗格局,为患有这些复杂病症的患者带来新希望。本综述旨在阐明STAR在现代心律失常管理中的重要性,并鼓励对这一开创性技术进行进一步探索和临床应用。

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