Pitkin Mark R
Department of Orthopaedics & Rehabilitation Medicine, Tufts University School of Medicine, Boston, MA 02111, USA.
Poly-Orth International, Sharon, MA 02067, USA.
Biomimetics (Basel). 2024 Apr 8;9(4):222. doi: 10.3390/biomimetics9040222.
Chronic overloading of the cartilage can lead to its irreversible destruction, as observed in people with osteoarthritis. The floating skeleton model previously introduced postulates that overloading begins and progresses when a joint is isolated from the hydrostatical connection with other joints. Such a connection occurs via the interstitial fluid in subperiosteal space and allows for pressure transmission between synovial capsules modulating intra-articular pressure. In the current study, a simple experiment was performed to model an obstruction in the subperiosteal hydrostatic pressure conductivity between joints to illustrate the effect of that obstruction on loads borne by the joint. When the obstruction was removed, the load experienced by the joint was reduced as it was redistributed throughout the model structure. The experiment demonstrated that contact pressures can be redistributed when the conditions of Pascal's Law are met.
正如骨关节炎患者所观察到的那样,软骨的长期过度负荷会导致其不可逆转的破坏。先前提出的浮动骨骼模型假定,当一个关节与其他关节的流体静力连接被隔离时,过度负荷就会开始并发展。这种连接通过骨膜下间隙中的组织液发生,并允许在滑膜囊之间传递压力,从而调节关节内压力。在当前的研究中,进行了一个简单的实验来模拟关节间骨膜下流体静压传导性的阻塞,以说明该阻塞对关节所承受负荷的影响。当阻塞被消除时,关节所承受的负荷会降低,因为它会重新分布到整个模型结构中。该实验表明,当满足帕斯卡定律的条件时,接触压力可以重新分布。