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艾滋病病毒/艾滋病感染者的痛苦耐受力与精神健康对抗逆转录病毒治疗依从性的关系。

The Relationship between Distress Tolerance and Spiritual Well-Being towards ARV Therapy Adherence in People Living with HIV/AIDS.

作者信息

Saputra Ramal, Waluyo Agung, Edison Chiyar

机构信息

Faculty of Nursing, Universitas Indonesia, Depok 16424, Indonesia.

出版信息

Healthcare (Basel). 2024 Apr 16;12(8):839. doi: 10.3390/healthcare12080839.

Abstract

A crucial factor in the success of treatment for patients with Human Immunodeficiency Virus (HIV) is adherence to antiretroviral (ARV) therapy among People Living with HIV/AIDS (PLWHA). Adherence issues remain a persisting problem with multifaceted causes. There are many studies on variables related to ARV therapy adherence, but no study has been found on spiritual well-being and distress tolerance in ARV therapy adherence. This study aims to determine the relationship between distress tolerance and spiritual well-being on adherence to ARV therapy in PLWHA. This research used a quantitative approach with a cross-sectional design. The sample collection process followed a consecutive sampling technique, with data gathered from 129 participants at the South Lampung Regional General Hospital located in Indonesia. Data collection was conducted using three questionnaires administered by the interviewer, which assessed distress tolerance using the Miller-Smith Rating Scale For Stress Tolerance (MSRS-ST), evaluated spiritual Well-Being using the Spiritual Well-Being Scale (SWBS), and gauged ARV therapy adherence using the Medication Adherence Rating Scale (MARS). Data analysis using a simple logistic regression with a 95% confidence interval (CI) showed a significant relationship between distress tolerance (-value 0.002) and spiritual well-being (-value 0.036) towards ARV therapy adherence in PLWHA. The results of multiple logistic regression yielded distress tolerance as the most dominant and influential variable in this research. Distress tolerance and spiritual well-being impact adherence to ARV therapy in PLWHA. Suggestions for healthcare services should consider these factors to decrease the risk of non-adherence to therapy and inadvertently heighten mortality risk.

摘要

对人类免疫缺陷病毒(HIV)患者治疗成功的一个关键因素是艾滋病毒/艾滋病感染者(PLWHA)坚持抗逆转录病毒(ARV)治疗。坚持治疗的问题仍然是一个多方面原因导致的持续存在的问题。关于与ARV治疗依从性相关的变量有很多研究,但尚未发现关于ARV治疗依从性中的精神幸福感和痛苦耐受力的研究。本研究旨在确定PLWHA中痛苦耐受力和精神幸福感与ARV治疗依从性之间的关系。本研究采用定量研究方法,采用横断面设计。样本收集过程采用连续抽样技术,数据来自印度尼西亚楠榜地区总医院的129名参与者。数据收集使用由访谈者管理的三份问卷,使用米勒 - 史密斯压力耐受力评定量表(MSRS - ST)评估痛苦耐受力,使用精神幸福感量表(SWBS)评估精神幸福感,并使用药物依从性评定量表(MARS)衡量ARV治疗依从性。使用95%置信区间(CI)的简单逻辑回归进行数据分析,结果显示痛苦耐受力(p值0.002)和精神幸福感(p值0.036)与PLWHA的ARV治疗依从性之间存在显著关系。多元逻辑回归结果表明,痛苦耐受力是本研究中最主要和最有影响力的变量。痛苦耐受力和精神幸福感会影响PLWHA对ARV治疗的依从性。医疗服务建议应考虑这些因素,以降低不坚持治疗的风险,并避免无意中增加死亡风险。

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