Chamroonsawasdi Kanittha, Insri Nittaya, Pitikultang Supachai
Department of Family Health, Mahidol University Bangkok, Thailand.
J Med Assoc Thai. 2011 Jul;94(7):775-81.
Cross-sectional survey research aimed at studying predictive factors of antiretroviral (ARV) drug adherence among people living with HIV/AIDS (PWHA) who attended Tawan Mai, an outpatient clinic, Taksin Hospital, Bangkok.
The sample group was 230 PWHA. A random sampling technique was used to select the sample. Data were collected by interview questionnaire between July 1, and September 30, 2009. The data was analyzed by frequency, percentage, mean, standard deviation, Pearson's Product Moment Correlation, and stepwise multiple regression analysis.
The results showed that 61.8% of the PWHA had a good level ofARV drug adherence. Factors significantly predicting ARV drug adherence (p < 0.05) were family support, perception on severity ofHIV/AIDS, adverse effects of the ARV drug, and knowledge on HIV/AIDS and AR V therapy. These factors were able to predict ARV drug adherence correctly at 26.8%.
From these findings, the authors recommend health providers to encourage family members to give family support to PWHA and to provide PWHA with more knowledge on HIV/AIDS and ARV therapy to enhance more self awareness for treatment adherence as well as to raise the perception on HIV/AIDS severity and adverse effects of ARV drug.
开展横断面调查研究，旨在探究在曼谷他信医院门诊Tawan Mai就诊的艾滋病毒/艾滋病患者（PWHA）中抗逆转录病毒（ARV）药物依从性的预测因素。
样本组为230名艾滋病毒/艾滋病患者。采用随机抽样技术选取样本。于2009年7月1日至9月30日期间通过访谈问卷收集数据。数据通过频率、百分比、均值、标准差、皮尔逊积矩相关分析和逐步多元回归分析进行分析。
结果显示，61.8%的艾滋病毒/艾滋病患者抗逆转录病毒药物依从性良好。显著预测抗逆转录病毒药物依从性的因素（p < 0.05）为家庭支持、对艾滋病毒/艾滋病严重程度的认知、抗逆转录病毒药物的不良反应以及对艾滋病毒/艾滋病和抗逆转录病毒治疗的知识。这些因素能够正确预测抗逆转录病毒药物依从性的比例为26.8%。
基于这些研究结果，作者建议医疗服务提供者鼓励家庭成员给予艾滋病毒/艾滋病患者家庭支持，并为患者提供更多关于艾滋病毒/艾滋病和抗逆转录病毒治疗的知识，以增强其治疗依从性的自我意识，同时提高对艾滋病毒/艾滋病严重程度和抗逆转录病毒药物不良反应的认知。
