Division of Pulmonary, Allergy and Sleep Medicine, Mayo Clinic in Florida, Jacksonville, Florida, USA
Pontificia Universidad Católica Argentina, Buenos Aires, Buenos Aires, Argentina.
BMJ Case Rep. 2024 Apr 25;17(4):e256573. doi: 10.1136/bcr-2023-256573.
A woman in her late 60s with severe chronic obstructive pulmonary disease (COPD) and emphysema underwent bronchoscopic lung volume reduction (BLVR) with endobronchial valves (EBV) to address hyperinflation. The initial EBV placement has led to partial lobar atelectasis of the left lower lobe and resulted in significant improvement in the patient's symptoms and lung function. However, valve migration occurred later due to pneumothorax unrelated to valves, leading to suboptimal clinical improvement. The patient achieved delayed full lobar atelectasis 21 months after EBV placement, which led to a significant clinical improvement. The patient decided to be delisted from the lung transplant list due to the improvement. This case highlights the importance of considering delayed atelectasis as a possible outcome of EBV placement and suggests the need for further exploration of the long-term implications and associations of this procedure.
一位 60 多岁的女性,患有严重的慢性阻塞性肺疾病(COPD)和肺气肿,接受了支气管镜下肺减容术(BLVR)和支气管内瓣膜(EBV)治疗以解决过度充气。最初的 EBV 放置导致左下叶部分肺段肺不张,并显著改善了患者的症状和肺功能。然而,后来由于与瓣膜无关的气胸发生了瓣膜迁移,导致临床改善不理想。患者在 EBV 放置后 21 个月出现延迟性全肺段肺不张,导致显著的临床改善。患者决定因改善而从肺移植名单中除名。本病例强调了将延迟性肺不张视为 EBV 放置可能结果的重要性,并提示需要进一步探讨该手术的长期影响和关联。